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HSPA12A Antibody, Biotin conjugated

  • 中文名稱：
    HSPA12A兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA010817LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HSPA12A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HSPA12A
  • 別名：
    FLJ13874 antibody; Heat shock 70 kDa protein 12A antibody; heat shock 70kD protein 12A antibody; heat shock 70kDa protein 12A antibody; HS12A_HUMAN antibody; Hspa12a antibody; KIAA0417 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Heat shock 70 kDa protein 12A protein (2-231AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization.
  • 基因功能參考文獻：
    1. The genotype "A/G" of rs1665650 in HSPA12A gene was associated with a decreased risk of gastric cancer. PMID: 26302849
    2. High BCLC staging scores, advanced cirrhosis and the overexpression of HSPA12A and HSP90B1 might be associated with poor survival from HCC, whereas high levels of HSPA4, HSPA5 and HSPA6 might be associated with earlier recurrence of HCC PMID: 25798051
    3. We found that HSPA12A is expressed in the human brain and shows a neuron- and region-specific transcript distribution, with strongest expression in the frontal and occipital cortical regions. HSPA12A Mrna was significantly reduced in schizophrenia. PMID: 15601604
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 17601350
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 18977241

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  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Heat shock protein 70 family
  • 組織特異性：
    Widely expressed with highest levels in brain, kidney and muscle.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19022

    OMIM: 610701

    KEGG: hsa:259217

    STRING: 9606.ENSP00000358211

    UniGene: Hs.648448