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KCTD1 Antibody, Biotin conjugated

  • 中文名稱：
    KCTD1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA744477LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) KCTD1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KCTD1
  • 別名：
    KCTD1 antibody; C18orf5 antibody; BTB/POZ domain-containing protein KCTD1 antibody; Potassium channel tetramerization domain-containing protein 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human BTB/POZ domain-containing protein KCTD1 protein (1-257AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.
  • 基因功能參考文獻：
    1. results reveal a novel role for Cu(2+) in determining the structure and function of KCTD1 PMID: 27596723
    2. The authors find that the KCTD proteins 5, 6, 9 and 17 bind to Cul3 with high affinity, while the KCTD proteins 1 and 16 do not have detectable binding. PMID: 26334369
    3. KCTD1 functions as a novel inhibitor of Wnt signaling p PMID: 24736394
    4. Mutations in KCTD1 cause scalp-ear-nipple syndrome. PMID: 23541344
    5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    6. indicate the novel function of KCTD1 as the transcriptional repressor for AP-2 family, especially for AP-2alpha PMID: 19115315

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  • 相關(guān)疾病：
    Scalp-ear-nipple syndrome (SENS)
  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in mammary gland, kidney, brain and ovary.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18249

    OMIM: 181270

    KEGG: hsa:284252

    STRING: 9606.ENSP00000408405

    UniGene: Hs.526630