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  4. LIME1 Antibody, FITC conjugated

LIME1 Antibody, FITC conjugated

  • 中文名稱：
    LIME1兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA884463LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LIME1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LIME1
  • 別名：
    LIME1 antibody; LIME antibody; LP8067 antibody; Lck-interacting transmembrane adapter 1 antibody; Lck-interacting membrane protein antibody; Lck-interacting molecule antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Lck-interacting transmembrane adapter 1 protein (170-295AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產品評價

靶點詳情

  • 功能：
    Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T-cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules.
  • 基因功能參考文獻：
    1. these results establish LIME as a transmembrane adaptor protein linking TCR stimulation to IS formation and integrin activation through activation of Vav(Vav guanine nucleotide exchange factor) PMID: 22395814
  • 亞細胞定位：
    Cell membrane; Single-pass type III membrane protein. Note=Present in lipid rafts. Recruited to the immunological synapse upon conjugation of T-cell with antigen-presenting cell.
  • 組織特異性：
    Expressed in peripheral blood lymphocytes, lymphoid tissues, and liver. Present in T-cells and plasma cells, and in various hematopoietic cell lines (at protein level).
  • 數(shù)據庫鏈接：

    HGNC: 26016

    OMIM: 609809

    KEGG: hsa:54923

    STRING: 9606.ENSP00000309521

    UniGene: Hs.233220