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LPHN1 Antibody

  • 中文名稱(chēng)：
    LPHN1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA008270
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Calcium independent alpha latrotoxin receptor 1 antibody; Calcium-independent alpha-latrotoxin receptor 1 antibody; CIRL-1 antibody; CIRL1 antibody; CL1 antibody; CLIBA antibody; G protein-coupled receptor for alpha-Latrotoxin antibody; KIAA0821 antibody; Latrophilin 1 antibody; Latrophilin-1 antibody; Latrophilin1 antibody; LEC2 antibody; Lectomedin 2 antibody; Lectomedin-2 antibody; LPHN 1 antibody; LPHN1 antibody; LPHN1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Latrophilin-1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:200-1:1000
    ELISA 1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis.
  • 基因功能參考文獻(xiàn)：
    1. alterations in latrophilin expression occur in AML cells expressing P-gp PMID: 29938681
    2. Our findings demonstrate that latrophilin-1 could be considered as a novel biomarker of human acute myeloid leukaemia PMID: 27322212
    3. A single SNP in LPHN1 (rs3810256) was identified, with the minor allele increasing the risk of asthma. PMID: 27325752
    4. In this article they evaluated the amount of p120-p85 complex still presented on the cellular membrane and confirmed that on cell surface major amount of mature CIRL-1 presented as a p120-p85 subunit complex. PMID: 20971062
  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, growth cone. Cell junction, synapse. Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, synaptosome.
  • 蛋白家族：
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 20973

    OMIM: 616416

    KEGG: hsa:22859

    STRING: 9606.ENSP00000340688

    UniGene: Hs.94229