Your Good Partner in Biology Research

MAFF Antibody

  • 中文名稱:
    MAFF兔多克隆抗體
  • 貨號(hào):
    CSB-PA013318GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    MAFF
  • 別名:
    Avian musculoaponeurotic fibrosarcoma virus (v maf) AS42 oncogene, protein F antibody; CTA 447C4.1 antibody; hMafF antibody; MAFF antibody; MAFF_HUMAN antibody; OTTHUMP00000199299 antibody; Transcription factor MafF antibody; U MAF antibody; U-Maf antibody; V maf avian musculoaponeurotic fibrosarcoma oncogene family, protein F antibody; V maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) antibody; V maf musculoaponeurotic fibrosarcoma oncogene homolog F antibody; V-maf musculoaponeurotic fibrosarcoma oncogene homolog F antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human MAFF
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition.
  • 基因功能參考文獻(xiàn):
    1. MAF genes have different levels of biological and genetic relevance. Besides, MAFF and MAFG could be associated with the susceptibility to develop CML. PMID: 24118457
    2. MafF/NFE2 hetrodimers act as weak transcriptional activators, and, in particular, are able to stimulate activity of the GCS1 promoter. PMID: 12490281
    3. In myometrial cells we observed an important induction by interleukin 1 beta and a weaker upregulation by tumor necrosis factor, whereas interleukin 6 treatment had no effect. PMID: 16371591
    4. Expression of hMafF or MIP alone did not alter basal reporter transcription activity, whereas co-expression of hMafF and MIP activated transcription efficiently. PMID: 16549056
    5. Only in the presence of both MIP and hMafF could the nUS2-pLacZi reporter in yeast genome be activated. PMID: 19723544

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    BZIP family, Maf subfamily
  • 組織特異性:
    Expressed in the term myometrium and kidney.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 6780

    OMIM: 604877

    KEGG: hsa:23764

    STRING: 9606.ENSP00000345393

    UniGene: Hs.517617