MDH1 Antibody
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中文名稱:MDH1兔多克隆抗體
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貨號:CSB-PA013621ESR1HU
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規(guī)格:¥440
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促銷:
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圖片:
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Western blot
All lanes: MDH1 antibody at 4μg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 37, 28, 39 kDa
Observed band size: 37 kDa -
Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA013621ESR1HU at dilution of 1:100
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Immunoprecipitating MDH1 in HepG2 whole cell lysate
Lane 1: Rabbit control IgG instead of (1μg) instead of CSB-PA013621ESR1HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the Secondary antibody (1/50000)
Lane 2: CSB-PA013621ESR1HU (4μg) + HepG2 whole cell lysate (500μg)
Lane 3: HepG2 whole cell lysate (20μg)
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) MDH1 Polyclonal antibody
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Uniprot No.:
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基因名:MDH1
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別名:cytoplasmic antibody; Cytosolic malate dehydrogenase antibody; Diiodophenylpyruvate reductase antibody; Malate dehydrogenase 1, NAD (soluble) antibody; Malate dehydrogenase antibody; Malate dehydrogenase cytoplasmic antibody; MDH s antibody; mdh1 antibody; MDHA antibody; MDHC_HUMAN antibody; MDHs antibody; MGC:1375 antibody; MOR2 antibody; Soluble malate dehydrogenase antibody
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宿主:Rabbit
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反應種屬:Human, Mouse
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免疫原:Recombinant Human Malate dehydrogenase, cytoplasmic protein (1-334AA)
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免疫原種屬:Homo sapiens (Human)
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標記方式:Non-conjugated
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:Antigen Affinity Purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式:Liquid
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應用范圍:ELISA, WB, IHC, IP
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推薦稀釋比:
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 IP 1:200-1:2000 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關產(chǎn)品
靶點詳情
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功能:Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH. Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation.
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基因功能參考文獻:
- expression of miR-126-5p suppresses the enzymatic activity of MDH1, mitochondrial respiration and caused cell death in non-small cell lung carcinoma cell lines. PMID: 29574159
- Data show that in the endogenous readthrough of the human MDH1 stop codon, the stop codon can encode tryptophan and arginine, and is tissue-specific. PMID: 27881739
- Proliferating cells rely on both MDH1 and LDH to replenish cytosolic NAD. PMID: 28263970
- Arginine methylation of MDH1 by CARM1 regulates cellular redox homeostasis and suppresses glutamine metabolism of pancreatic cancer. PMID: 27840030
- adipogenic differentiation may be regulated by the acetylation of MDH1 PMID: 22693256
- The MDH1 gene is not the cause of RP28-linked autosomal recessive retinitis pigmentosa. PMID: 20011630
- expression of MDH1 is maintained in the adult heart but is not present in levels as high as in the fetus PMID: 15565635
- Malate Dehydrogenase directly regulates the Tumor Suppressor Protein p53-dependent apoptosis upon glucose deprivation and involved in maintaining cellular metabolic state and further determining cell death. PMID: 19229245
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亞細胞定位:Cytoplasm.
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蛋白家族:LDH/MDH superfamily, MDH type 2 family
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數(shù)據(jù)庫鏈接:
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