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  4. MED4 Antibody, Biotin conjugated

MED4 Antibody, Biotin conjugated

  • 中文名稱：
    MED4兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA865098LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MED4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MED4
  • 別名：
    Activator-recruited cofactor 36 kDa component antibody; ARC36 antibody; DRIP36 antibody; FLJ10956 antibody; HSPC126 antibody; med4 antibody; MED4_HUMAN antibody; Mediator complex subunit 4 antibody; Mediator of RNA polymerase II transcription subunit 4 antibody; Mediator of RNA polymerase II transcription, subunit 4 homolog antibody; OTTHUMP00000018390 antibody; OTTHUMP00000018391 antibody; OTTHUMP00000018392 antibody; RP11-90M2.2 antibody; TRAP/SMCC/PC2 subunit p36 subunit antibody; TRAP36 antibody; VDRIP antibody; Vitamin D3 receptor-interacting protein complex 36 kDa component antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Mediator of RNA polymerase II transcription subunit 4 protein (167-270AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • 基因功能參考文獻(xiàn)：
    1. retinoblastoma RB1 -/- cells cannot survive in the absence of MED4, both in vitro and in orthotopic xenograft models in vivo, therefore identifying MED4 as a survival gene in retinoblastoma. PMID: 24858910
    2. Our findings suggest that Vitamin D Receptor polymorphisms may be associated with nasal carriage of S. aureus in individuals with type 1 diabetes. PMID: 19411183
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Mediator complex subunit 4 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17903

    OMIM: 605718

    KEGG: hsa:29079

    STRING: 9606.ENSP00000258648

    UniGene: Hs.181112