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MILR1 Antibody

  • 中文名稱：
    MILR1兔多克隆抗體
  • 貨號：
    CSB-PA801819LA01HU
  • 規(guī)格：
    ￥440
  • 促銷：
    小規(guī)格抗體限時一口價
  • 圖片：
    • Western blot
      All lanes: MILR1 antibody at 14 μg/ml
      Lane 1: Mouse brain tissue
      Lane 2: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 39, 28, 29 kDa
      Observed band size: 39, 120 kDa
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA801819LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA801819LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MILR1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MILR1
  • 別名：
    Allergin-1 antibody; Allergy inhibitory receptor 1 antibody; C17orf60 antibody; Mast cell antigen 32 antibody; Mast cell immunoglobulin-like receptor 1 antibody; MCA-32 antibody; MCA32 antibody; MILR1 antibody; MILR1_HUMAN antibody; Probable mast cell antigen 32 homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Allergin-1 protein (249-343AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，MILR1 Antibody (CSB-PA801819LA01HU)，的標記方式是Non-conjugated。對于MILR1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA801819LB01HU MILR1 Antibody, HRP conjugated ELISA
    FITC CSB-PA801819LC01HU MILR1 Antibody, FITC conjugated
    Biotin CSB-PA801819LD01HU MILR1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產品評價

靶點詳情

  • 功能：
    Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction.
  • 基因功能參考文獻：
    1. Data indicate that the rs6504230 polymorphism affects MILR1 (mast cell immunoglobulin-like receptor 1; synonyms, Allergin-1) expression levels, leading to a susceptibility to producing specific IgE antibodies against common allergens. PMID: 25007884
    2. Allergin-1S1, a splicing isoform of Allergin-1, is predominantly expressed on human primary MC in both bronchoalveolar lavage fluid and nasal scratching specimens. Moreover, Allergin-1S1 inhibits IgE-mediated activation from human primary MC in BAL fluid. PMID: 24116093
    3. It is a immunoglobulin-like receptor which regulates the activation of mast cell.(review) PMID: 24552759
  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Expressed in myeloid cells (dendritic cells, macrophages and neutrophils, weak expression on B-cells but not in T-cells or natural killer cells), peripheral blood basophils and mast cells (at protein level).
  • 數據庫鏈接：

    HGNC: 27570

    KEGG: hsa:284021

    UniGene: Hs.631749