Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MT1G Antibody, HRP conjugated

MT1G Antibody, HRP conjugated

  • 中文名稱：
    MT1G兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA17384B0Rb
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MT1G Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MT1G
  • 別名：
    Metallothionein-1G antibody; Metallothionein-1K antibody; Metallothionein-IG antibody; MT-1G antibody; MT-1K antibody; MT-IG antibody; MT1G antibody; MT1G_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Metallothionein-1G protein (1-59AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
  • 基因功能參考文獻(xiàn)：
    1. These findings indicate that MT1 constitute a biomarker adapted for exploring the impact of sorafenib on the redox metabolism of cancer cells. PMID: 27184800
    2. A new tumor-suppressor activity of MT1G in colorectal cancer cells.MT1G role in cell differentiation. PMID: 28393194
    3. PU.1 suppressive target gene, metallothionein 1G, inhibits retinoic acid-induced NB4 cell differentiation PMID: 25072246
    4. MT1G was down-regulated in renal cell carcinogenesis. PMID: 24662736
    5. MT1M and MT1G promoter methylation may be used as serum biomarkers for noninvasive detection of hepatocellular carcinoma. PMID: 24782625
    6. Metallothionein 1G and zinc sensitize human colorectal cancer cells to chemotherapy. PMID: 24634414
    7. Metallothionein 1G functions as a tumor suppressor in thyroid cancer through modulating the PI3K/Akt signaling pathway. PMID: 24098937
    8. GPR56, MT1G, and RASSF1 might be the potential methylation markers associated with acquired multidrug resistance of lung adenocarcinoma. PMID: 23902976
    9. Results describe MT1G promoter hypermethylation in hepatoblastoma and demonstrate that aberrant methylation is a frequent event in this malignancy. PMID: 20032811
    10. Loss of metallothionein 1G function due to hypermethylation of its promoter leads to athogenesis of papillary thyroid carcinoma PMID: 12640681
    11. Induction of the hMT1G promoter by VEGF and heavy metals occurs through the utilization of different transcription factors. PMID: 15735762
    12. Eight MT genes were up-regulated after treatment of T-ALL cells with 0.15 and 1.5 microg/mL of metal ores. Heavy metal binding activity. PMID: 15747776
    13. MT1G is hypermethylated in renal cell carcinoma. PMID: 18639284
    14. Using a panel of four genes (AHRR, p16INK4a, MT1G, and CLDN3) resulted in sensitivity and specificity of 50% and 68%, respectively and may have utility for early detection of esophageal squamous dysplasia and early ESCC. PMID: 19137073
    15. Promoter methylation and differential gene expression of five markers: COL1A2, NPM2, HSPB6, DDIT4L and MT1G were validated by sequencing of bisulfite-modified DNA and real-time reverse transcriptase PCR, respectively. PMID: 19491193
    16. p16INK4A, DAPK1, PTEN and MT1G genes were not frequently methylated in the stage I non-small cell lung cancer in China. PMID: 19506903
    17. MT1G acts as a tumor suppressor gene in hepatocellular carcinoma PMID: 19639168

    顯示更多

    收起更多

  • 蛋白家族：
    Metallothionein superfamily, Type 1 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 7399

    OMIM: 156353

    KEGG: hsa:4495

    STRING: 9606.ENSP00000391397

    UniGene: Hs.433391