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MTERF4 Antibody, FITC conjugated

  • 中文名稱：
    MTERF4兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA800224LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MTERF4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MTERF4
  • 別名：
    FLJ16261 antibody; HSPC096 antibody; MGC61716 antibody; MTER2_HUMAN antibody; MTERF domain containing 2 antibody; mTERF domain-containing protein 2 antibody; Mterfd2 antibody; OTTHUMP00000200479 antibody; OTTHUMP00000200519 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Transcription termination factor 4, mitochondrial protein (45-87AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S and targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit (39S).
  • 基因功能參考文獻：
    1. The overexpression of MTERF4 induced a significant increase in the levels of APP protein and secreted Abeta 42 in HEK293-APPswe cells compared with control cells these results suggest that MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10 in HEK293-APPswe cells; therefore, MTERF4 may play an important role in the pathogenesis of Alzheimer's disease. PMID: 27894840
    2. analysis of the 3D crystal structure of the human MTERF4-NSUN4 complex PMID: 22949673
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    MTERF family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 28785

    OMIM: 615393

    KEGG: hsa:130916

    STRING: 9606.ENSP00000241527

    UniGene: Hs.159556