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MTPN Antibody

  • 中文名稱:
    MTPN兔多克隆抗體
  • 貨號:
    CSB-PA015195GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    MTPN
  • 別名:
    FLJ31098 antibody; FLJ99857 antibody; GCDP antibody; Granule cell differentiation protein antibody; mtpn antibody; MTPN_HUMAN antibody; Myotrophin antibody; Protein V 1 antibody; Protein V-1 antibody; V 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human MTPN
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能:
    Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy.
  • 基因功能參考文獻:
    1. In our findings 9cRA emerges has a hormone with a regulatory action on miR-375 that in most cases interfere with Mtpn expression. PMID: 28300567
    2. T allele of rs17168525 in the 3'-UTR of myotrophin influence the level of myotrophin protein by interfering with let-7 binding.The T allele of MTPN rs17168525 is not associated with the left ventricular hypertrophy risk in essential hypertension patients. PMID: 26274321
    3. myotrophin/V-1 is a regulatory protein for modulating the levels of activated NFkappaB dimers. PMID: 11971907
    4. a novel internal ribosome entry site-mediated mechanism may be responsible for the translation of unconventional self-Ag MPD6 in response to IFN-alpha stimulation. PMID: 16982933
  • 亞細胞定位:
    Cytoplasm. Nucleus. Cytoplasm, perinuclear region.
  • 蛋白家族:
    Myotrophin family
  • 組織特異性:
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 15667

    OMIM: 606484

    KEGG: hsa:136319

    STRING: 9606.ENSP00000376800

    UniGene: Hs.602015