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MTPN Antibody

  • 中文名稱：
    MTPN兔多克隆抗體
  • 貨號：
    CSB-PA015195GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    MTPN
  • 別名：
    FLJ31098 antibody; FLJ99857 antibody; GCDP antibody; Granule cell differentiation protein antibody; mtpn antibody; MTPN_HUMAN antibody; Myotrophin antibody; Protein V 1 antibody; Protein V-1 antibody; V 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human MTPN
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy.
  • 基因功能參考文獻：
    1. In our findings 9cRA emerges has a hormone with a regulatory action on miR-375 that in most cases interfere with Mtpn expression. PMID: 28300567
    2. T allele of rs17168525 in the 3'-UTR of myotrophin influence the level of myotrophin protein by interfering with let-7 binding.The T allele of MTPN rs17168525 is not associated with the left ventricular hypertrophy risk in essential hypertension patients. PMID: 26274321
    3. myotrophin/V-1 is a regulatory protein for modulating the levels of activated NFkappaB dimers. PMID: 11971907
    4. a novel internal ribosome entry site-mediated mechanism may be responsible for the translation of unconventional self-Ag MPD6 in response to IFN-alpha stimulation. PMID: 16982933
  • 亞細胞定位：
    Cytoplasm. Nucleus. Cytoplasm, perinuclear region.
  • 蛋白家族：
    Myotrophin family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 15667

    OMIM: 606484

    KEGG: hsa:136319

    STRING: 9606.ENSP00000376800

    UniGene: Hs.602015