NEK4 Antibody
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中文名稱:NEK4兔多克隆抗體
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貨號:CSB-PA015702LA01HU
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規(guī)格:¥440
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促銷:
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圖片:
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Immunofluorescence staining of Hela cells with CSB-PA015702LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) NEK4 Polyclonal antibody
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Uniprot No.:
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基因名:NEK4
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別名:NEK4 antibody; STK2 antibody; Serine/threonine-protein kinase Nek4 antibody; EC 2.7.11.1 antibody; Never in mitosis A-related kinase 4 antibody; NimA-related protein kinase 4 antibody; Serine/threonine-protein kinase 2 antibody; Serine/threonine-protein kinase NRK2 antibody
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宿主:Rabbit
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反應種屬:Human
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免疫原:Recombinant Human Serine/threonine-protein kinase Nek4 protein (516-661AA)
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免疫原種屬:Homo sapiens (Human)
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標記方式:Non-conjugated
本頁面中的產(chǎn)品,NEK4 Antibody (CSB-PA015702LA01HU),的標記方式是Non-conjugated。對于NEK4 Antibody,我們還提供其他標記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應用范圍:ELISA, IF
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推薦稀釋比:
Application Recommended Dilution IF 1:50-1:200 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
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功能:Protein kinase that seems to act exclusively upon threonine residues. Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cycle arrest in response to double-stranded DNA damage.
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基因功能參考文獻:
- High NEK4 expression is associated with lung cancer and colorectal cancer. PMID: 27602754
- Nek4 as a novel regulator of replicative senescence and the response to double-stranded DNA damage. PMID: 22851694
- Nek4 interaction with both RPGRIP1 and the RPGRIP1L is involved in cilium assembly. PMID: 21685204
- Data show that after Taxol treatment, Nek4 promoted microtubule outgrowth, whereas Nek4 deficiency impaired G(2)-M arrest and decreased formation of mitotic-like asters. PMID: 20103636
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亞細胞定位:Cell projection, cilium. Cytoplasm.
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蛋白家族:Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily
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組織特異性:Highest expression in adult heart, followed by pancreas, skeletal muscle, brain, testis, retina, liver, kidney, lung and placenta. Present in most primary carcinomas.
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