NKIRAS1 Antibody, Biotin conjugated
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中文名稱(chēng):NKIRAS1兔多克隆抗體, Biotin偶聯(lián)
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規(guī)格:¥880
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱(chēng):Rabbit anti-Homo sapiens (Human) NKIRAS1 Polyclonal antibody
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Uniprot No.:
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基因名:NKIRAS1
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別名:2400004O09Rik antibody; I kappa B interacting Ras like protein 1 antibody; I-kappa-B-interacting Ras-like protein 1 antibody; Kappa B Ras 1 antibody; Kappa B Ras protein 1 antibody; Kappa B-Ras protein 1 antibody; KappaB Ras1 antibody; KappaB-Ras1 antibody; KBRAS 1 antibody; KBRAS1 antibody; KBRS1_HUMAN antibody; NF kappa B inhibitor interacting Ras like protein 1 antibody; NF-kappa-B inhibitor-interacting Ras-like protein 1 antibody; NFKB inhibitor interacting Ras like 1 antibody; NFKB inhibitor interacting Ras like protein 1 antibody; NKIRAS 1 antibody; nkiras1 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human NF-kappa-B inhibitor-interacting Ras-like protein 1 protein (1-192AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Biotin
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克隆類(lèi)型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA
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Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
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基因功能參考文獻(xiàn):
- It was demonstrated that elevated levels of mRNA for NKIRAS1 was significantly associated both with loss of methylation in NKIRAS1 CpG-islands and methylation in a number of miRNA genes. PMID: 25869366
- Significant correlation was found between alterations of methylation status of miR-34b/c, miR-193a and the expression level of NKIRAS1 target gene in the primary lung tumors. PMID: 23156677
- Low kappaB-Ras1 expression is associated with gliomas. PMID: 21302000
- It was shown the decreased expression level of NKIRAS1 in Renal cell carcinoma PMID: 20693965
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亞細(xì)胞定位:Cytoplasm.
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蛋白家族:Small GTPase superfamily, Ras family, KappaB-Ras subfamily
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組織特異性:Widely expressed.
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數(shù)據(jù)庫(kù)鏈接:
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