NKX3-2 Antibody
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中文名稱:NKX3-2兔多克隆抗體
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貨號:CSB-PA015849LA01HU
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規(guī)格:¥440
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促銷:
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圖片:
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) NKX3-2 Polyclonal antibody
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Uniprot No.:
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基因名:NKX3-2
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別名:Bagpipe homeobox 1 antibody; Bagpipe homeobox homolog 1 antibody; Bagpipe homeobox protein homolog 1 antibody; Bagpipe homeobox; Drosophila; homolog of; 1 antibody; BAPX 1 antibody; Homeobox protein NK-3 homolog B antibody; Homeobox protein Nkx 3.2 antibody; Homeobox protein Nkx-3.2 antibody; MGC138171 antibody; NK3 homeobox 2 antibody; NKX3 2 antibody; NKX3-2 antibody; NKX3.2 antibody; NKX3.2; mouse; homolog of antibody; NKX32_HUMAN antibody; NKX3B antibody; OTTHUMP00000115816 antibody; SMMD antibody
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宿主:Rabbit
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反應(yīng)種屬:Human, Rat
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免疫原:Recombinant Human Homeobox protein Nkx-3.2 protein (1-333AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
本頁面中的產(chǎn)品,NKX3-2 Antibody (CSB-PA015849LA01HU),的標(biāo)記方式是Non-conjugated。對于NKX3-2 Antibody,我們還提供其他標(biāo)記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, WB
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:5000 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
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功能:Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus.
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基因功能參考文獻(xiàn):
- NKL homeobox gene NKX2-5 was activated by NKX3-2 in CCRF-CEM and by FOXG1 in PEER, representing mutually inhibitory activators of this translocated oncogene. PMID: 29746601
- post-translational modification of Nkx3.2 employing HDAC9-PIASy-RNF4 axis plays a crucial role in controlling chondrocyte viability and hypertrophic maturation during skeletal development in vertebrates. PMID: 27312341
- Bapx1 indicates poor prognosis for gastric cancer patients by promoting tumor migration and invasion via TGF-beta-induced epithelial-mesenchymal transition. PMID: 28315334
- PI3K-mediated suppression of Nkx3.2 in chondrocytes plays a role in the control of cartilage hypertrophy during skeletal development in vertebrates. PMID: 26363466
- Our findings indicate that BAPX-1/NKX-3.2 is a molecular switch that is involved in controlling the hypertrophic phenotype of the postdevelopmental (OA) articular chondrocyte. PMID: 26245691
- Ihh-induced Nkx3.2 degradation requires Wnt5a, which is capable of triggering Nkx3.2 degradation PMID: 22507129
- Data show that IkappaB kinase beta (IKKbeta) can be activated in the nucleus by Nkx3.2 in the absence of exogenous IKK-activating signals, allowing constitutive nuclear degradation of IkappaB-alpha. PMID: 21606193
- NKX3-2 plays an important role in endochondral ossification of both the axial and appendicular skeleton in humans PMID: 20004766
- Data show that Meox1 activates the Bapx1 promoter in a dose-dependent manner and that this activity is enhanced in the presence of Pax1 and/or Pax9. PMID: 15024065
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相關(guān)疾?。?/div>Spondylo-megaepiphyseal-metaphyseal dysplasia (SMMD)亞細(xì)胞定位:Nucleus.蛋白家族:NK-3 homeobox family組織特異性:Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton.數(shù)據(jù)庫鏈接:
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