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NXPH1 Antibody

  • 中文名稱：
    NXPH1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA009085
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    NXPH1
  • 別名：
    Nbla00697 antibody; Neurexophilin 1 antibody; Neurexophilin-1 antibody; Neurexophilin1 antibody; NPH1 antibody; NXPH 1 antibody; NXPH1 antibody; NXPH1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Neurexophilin-1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.
  • 基因功能參考文獻(xiàn)：
    1. identification of SNPs within the IQCJ, NXPH1, PHF17 and MYB genes partly explaining the large interindividual variability observed in plasma triglyceride levels in response to an n-3 fatty acid supplementation PMID: 27160456
    2. A genome-wide association study (GWAS) identified loci associated with the plasma triglyceride (TG) response to omega-3 fatty acid (FA) supplementation in IQCJ, NXPH1, PHF17 and MYB. PMID: 28134766
    3. The role of NXPH1 in in paranoid schizophrenia development in Russians. PMID: 26410934
    4. Rs2349775 (NXPH1) and rs17837965 (CDC42) were associated with diarrhoea and constipation predominant irritable bowel syndrome, respectively, in two independent cohorts. PMID: 24041540
    5. Data indicate that median methylation levels of BCAN, HOXD1, KCTD8, KLF11, NXPH1, POU4F1, SIM1, and TCF7L1 were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis. PMID: 22930747
    6. Data indicate taht candidate genes ACTB, BZW, OCM, MACC1, NXPH1, PRPS1L1, RAC1 and RPA3, which lie within the DFNB90 region, were sequenced and no potentially causal variants were identified. PMID: 21734401
    7. results demonstrate the presence and function of a regulated signaling axis in hematopoiesis centered on NRXN1alpha and its modulation by DAG1 and NXPH1 PMID: 21628410
    8. In rat, neurexophilin 1 forms a very tight complex with neurexin I alpha. PMID: 8699246
    9. In rat, the secreted ligand for alpha-neurexin, neurexophilin 1, is expressed in the postnatal olfactory bulb. PMID: 12141453

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  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Neurexophilin family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20693

    OMIM: 604639

    KEGG: hsa:30010

    STRING: 9606.ENSP00000384551

    UniGene: Hs.487564