OPN5 Antibody
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中文名稱:OPN5兔多克隆抗體
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貨號:CSB-PA740895LA01HU
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規(guī)格:¥440
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促銷:
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圖片:
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Immunofluorescent analysis of Hela cells using CSB-PA740895LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA740895LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA740895LA01HU at dilution of 1:100
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) OPN5 Polyclonal antibody
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Uniprot No.:
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基因名:
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別名:OPN5; GPR136; PGR12; TMEM13; Opsin-5; G-protein coupled receptor 136; G-protein coupled receptor PGR12; Neuropsin; Transmembrane protein 13
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human Opsin-5 protein (310-353AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
本頁面中的產(chǎn)品,OPN5 Antibody (CSB-PA740895LA01HU),的標(biāo)記方式是Non-conjugated。對于OPN5 Antibody,我們還提供其他標(biāo)記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, IHC, IF
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推薦稀釋比:
Application Recommended Dilution IHC 1:20-1:200 IF 1:50-1:200 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:G-protein coupled receptor which selectively activates G(i) type G proteins via ultraviolet A (UVA) light-mediated activation in the retina. Preferentially binds the chromophore 11-cis retinal and is a bistable protein that displays emission peaks at 380 nm (UVA light) and 470 nm (blue light). Required for the light-response in the inner plexiform layer, and contributes to the regulation of the light-response in the nerve fiber layer, via phosphorylated DAT/SLC6A3 dopamine uptake. Involved in local corneal and retinal circadian rhythm photoentrainment via modulation of the UVA light-induced phase-shift of the retina clock. Acts as a circadian photoreceptor in the outer ear, via modulation of circadian clock-gene expression in response to violet light during the light-to-dark transition phase and night phase of the circadian cycle. Required in the retina to negatively regulate hyaloid vessel regression during postnatal development via light-dependent OPN5-SLC32A1-DRD2-VEGFR2 signaling. Involved in the light-dependent regulation of retina and vitreous compartment dopamine levels.
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基因功能參考文獻(xiàn):
- Expression of the hNP gene on the mRNA level, evaluated based on peripheral blood, is significantly higher in the patients with MRD than in the healthy subjects. PMID: 28636578
- Data indicate that opsin5 (OPN5) photoreceptor mediates light-induced Ca(2+) response. PMID: 24941910
- It dissects a schizophrenic susceptibility gene, NRG1. PMID: 24614639
- Opn5m may work exclusively as a short wavelength sensor in the brain as well as in the retina with the assistance of an 11-cis-retinal-supplying system. PMID: 24403072
- UV photoreceptor in human beings OPN5 triggers a UV-sensitive Gi-mediated signaling pathway in the mammalian tissues. PMID: 22043319
- Genetic variation of the hNP gene may contribute to molecular mechanisms of bipolar disorder and some aspects of memory and intelligence. PMID: 18354391
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亞細(xì)胞定位:Cell membrane; Multi-pass membrane protein.
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蛋白家族:G-protein coupled receptor 1 family, Opsin subfamily
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組織特異性:Detected in brain and retina and cell lines derived from neural retina.
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數(shù)據(jù)庫鏈接:
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