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PCF11 Antibody, FITC conjugated

  • 中文名稱(chēng)：
    PCF11兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA017603LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) PCF11 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PCF11
  • 別名：
    hPCF11 antibody; KIAA0824 antibody; OTTHUMP00000234826 antibody; PCF11 antibody; PCF11 cleavage and polyadenylation factor subunit antibody; PCF11; cleavage and polyadenylation factor II subunit; homolog antibody; PCF11; cleavage and polyadenylation factor subunit; homolog (S. antibody; PCF11_HUMAN antibody; PCF11p homolog antibody; Pre-mRNA cleavage complex 2 protein Pcf11 antibody; Pre-mRNA cleavage complex II protein Pcf11 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Pre-mRNA cleavage complex 2 protein Pcf11 protein (409-604AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of pre-mRNA cleavage complex II.
  • 基因功能參考文獻(xiàn)：
    1. WNK1 and the associated phosphorylation of the PCF11 CID act to promote transcript release from chromatin-associated Pol II, which in turn facilitates mRNA export to the cytoplasm PMID: 29196535
    2. Pcf11 can act as a negative elongation factor to repress RNA Pol II gene expression in eukaryotic cells. PMID: 17606639
    3. Pcf11 is required for the efficient degradation of the 3' product of poly(A) site cleavage. PMID: 18086705
    4. Human PCf11 is a pre-mRNA processing factor. PMID: 11060040
  • 亞細(xì)胞定位：
    Nucleus.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 30097

    OMIM: 608876

    KEGG: hsa:51585

    STRING: 9606.ENSP00000298281

    UniGene: Hs.128959