PIK3R5 Antibody
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中文名稱:PIK3R5兔多克隆抗體
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貨號(hào):CSB-PA018008GA01HU
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規(guī)格:¥3,900
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:
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別名:5-bisphosphate 3-kinase regulatory subunit antibody; F730038I15Rik antibody; FOAP 2 antibody; FOAP2 antibody; OTTHUMP00000135339 antibody; p101 antibody; P101 PI3K antibody; p101-PI3K antibody; Phosphatidylinositol 4 antibody; Phosphatidylinositol 4,5 bisphosphate 3 kinase regulatory subunit antibody; Phosphoinositide 3 kinase, regulatory subunit 5 antibody; Phosphoinositide 3 kinase, regulatory subunit 5, p101 antibody; Phosphoinositide 3 kinase, regulatory subunit, polypeptide p101 antibody; Phosphoinositide 3-kinase regulatory subunit 5 antibody; PI3 kinase p101 subunit antibody; PI3 kinase regulatory subunit 5 antibody; PI3-kinase p101 subunit antibody; PI3-kinase regulatory subunit 5 antibody; PI3R5_HUMAN antibody; PIK3 R5 antibody; PIK3R5 antibody; Protein FOAP 2 antibody; Protein FOAP-2 antibody; PtdIns 3 kinase p101 antibody; PtdIns 3 kinase regulatory subunit antibody; PtdIns-3-kinase p101 antibody; PtdIns-3-kinase regulatory subunit antibody
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宿主:Rabbit
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反應(yīng)種屬:Human,Mouse,Rat
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免疫原:Human PIK3R5
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免疫原種屬:Homo sapiens (Human)
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抗體亞型:IgG
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純化方式:Antigen Affinity Purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA,WB,IF
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Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG.
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基因功能參考文獻(xiàn):
- data argue for differential regulatory functions of the non-catalytic subunits and a specific Gbetagamma-dependent regulation of p101 in PI3Kgamma activation. PMID: 26173259
- PIK3R5 promoter hypermethylation is associated with oral squamous cell carcinoma. PMID: 25374236
- expression and activities of PI3Kgamma are modified differently by p87 and p101 in vitro and in living cells, arguing for specific regulatory roles of the non-catalytic subunits in the differentiation of PI3Kgamma signaling pathways. PMID: 24014027
- Our characterization of the PIK3R5 protein and findings suggest that it may play a role in the development of the cerebellum and vermis. PMID: 22065524
- p101 has a role in membrane recruitment and activation of PI3K gamma PMID: 12507995
- analysis of functional domains in the p101 regulatory subunit of phosphoinositide 3-kinase gamma PMID: 15611065
- Overexpression of p101 activates PI3Kgamma signaling and is associated with T-cell lymphomas PMID: 17486067
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相關(guān)疾病:Ataxia-oculomotor apraxia 3 (AOA3)
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亞細(xì)胞定位:Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein.
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組織特異性:Ubiquitously expressed with high expression in fetal brain compared to adult brain. Abundant expression is observed in cerebellum, cerebral cortex, cerebral meninges, and vermis cerebelli.
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數(shù)據(jù)庫(kù)鏈接:
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