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PKD1L2 Antibody, FITC conjugated

  • 中文名稱：
    PKD1L2兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA773589LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PKD1L2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PKD1L2
  • 別名：
    PKD1L2 antibody; KIAA1879 antibody; PC1L2 antibody; Polycystic kidney disease protein 1-like 2 antibody; PC1-like 2 protein antibody; Polycystin-1L2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Polycystic kidney disease protein 1-like 2 protein (1-306AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    May function as an ion-channel regulator. May function as a G-protein-coupled receptor.
  • 基因功能參考文獻(xiàn)：
    1. Study found an association between a 6.2 kb dele- tion in the PKD1L2 gene and colorectal cancer in a Korean population. PMID: 27605020
    2. genes are mapped to chromosomes and gene structures are characterized; protein structure is predicted and contains strong ion channel signature motifs that suggest their possible function as components of cation channel pores PMID: 12782129
    3. PKD1L2 is expressed in the developing and adult heart and kidney. PMID: 15203210
    4. Ectopic expression of PKD1L2 in transgenic mice caused severe muscle atrophy. PMID: 19578180
  • 亞細(xì)胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Polycystin family
  • 組織特異性：
    Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 21715

    OMIM: 607894

    KEGG: hsa:114780

    STRING: 9606.ENSP00000469432

    UniGene: Hs.413525