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PPP2R5E Antibody, HRP conjugated

  • 中文名稱：
    PPP2R5E兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA619075LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PPP2R5E Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    2A5E_HUMAN antibody; Epsilon isoform of regulatory subunit B56 protein phosphatase 2A antibody; PP2A B subunit B' epsilon antibody; PP2A B subunit B' epsilon isoform antibody; PP2A B subunit B56 epsilon antibody; PP2A B subunit B56 epsilon isoform antibody; PP2A B subunit isoform B''-epsilon antibody; PP2A B subunit isoform B'-epsilon antibody; PP2A B subunit isoform B56-epsilon antibody; PP2A B subunit isoform PR61-epsilon antibody; PP2A B subunit isoform R5-epsilon antibody; PP2A B subunit PR61 epsilon antibody; PP2A B subunit PR61 epsilon isoform antibody; PP2A B subunit R5 epsilon antibody; PP2A B subunit R5 epsilon isoform antibody; PPP2R5E antibody; Protein phosphatase 2 regulatory subunit B (B56) epsilon isoform antibody; Protein phosphatase 2 regulatory subunit B' epsilon antibody; Protein phosphatase 2 regulatory subunit B' epsilon isoform antibody; Regulatory subunit B of protein phosphatase 2 epsilon isoform antibody; Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit epsilon antibody; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform protein (2-149AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
  • 基因功能參考文獻(xiàn)：
    1. results suggest that the PPP2R5E phosphatase may contribute to microtubule organization by stabilizing MTCL1. PMID: 27521566
    2. PP2A holoenzyme containing B56 is responsible for the dephosphorylation of gamma-H2AX and regulation of DNA repair of double strand breaks induced by camptothecin. PMID: 25772433
    3. the significance of miR-23a and PPP2R5E in the proliferation and apoptosis of gastric cancer cells PMID: 24997345
    4. Downregulation of PPP2R5E affects the oncogenic potential of leukemic cells. PMID: 23812941
    5. identified the phosphorylation of hSgo2 by Aurora B at the N-terminal coiled-coil region and the middle region, and showed that these phosphorylations separately promote binding of hSgo2 to PP2A and MCAK PMID: 20889715
    6. The PPP2R5E gene is identified as harboring genetic variants that can affect human cancer and are possibly under evolutionary selection pressure. PMID: 19773383

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  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Phosphatase 2A regulatory subunit B56 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 9313

    OMIM: 601647

    KEGG: hsa:5529

    STRING: 9606.ENSP00000337641

    UniGene: Hs.334868