PRKAB2 Antibody
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中文名稱:PRKAB2兔多克隆抗體
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貨號(hào):CSB-PA527326ESR1HU
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規(guī)格:¥440
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促銷(xiāo):
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圖片:
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) PRKAB2 Polyclonal antibody
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Uniprot No.:
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基因名:
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別名:5' AMP activated protein kinase beta 2 subunit antibody; 5' AMP activated protein kinase subunit beta 2 antibody; 5''-AMP-activated protein kinase subunit beta-2 antibody; AAKB2_HUMAN antibody; AMP activated protein kinase beta 2 non catalytic subunit antibody; AMPK beta 2 antibody; AMPK beta 2 chain antibody; AMPK subunit beta 2 antibody; AMPK subunit beta-2 antibody; MGC61468 antibody; PRKAB 2 antibody; Prkab2 antibody; Protein kinase AMP activated beta 2 non catalytic subunit antibody
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宿主:Rabbit
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反應(yīng)種屬:Human, Mouse, Rat
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免疫原:Recombinant Human 5\'-AMP-activated protein kinase subunit beta-2 protein (1-272AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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克隆類(lèi)型:Polyclonal
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抗體亞型:IgG
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純化方式:Antigen Affinity Purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, WB
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:2000 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
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基因功能參考文獻(xiàn):
- Sumoylation of AMPKbeta2 subunit enhances AMP-activated protein kinase activity. PMID: 23552691
- results of this study demonistrated that the novel findings that intronic SNPs in the genes coding for the regulatory beta2(PRKAB2) of AMPK are associated with antipsychotic-induced weight gain in schizophrenia or schizoaffective disorder patients PMID: 22305490
- variants in PRKAB2 are unlikely to contribute to the type 2 diabetes mellitus susceptibility in Pima Indians PMID: 12490143
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蛋白家族:5'-AMP-activated protein kinase beta subunit family
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數(shù)據(jù)庫(kù)鏈接:
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