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PRSS56 Antibody, Biotin conjugated

  • 中文名稱：
    PRSS56兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA317372LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PRSS56 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PRSS56
  • 別名：
    PRSS56 antibody; Serine protease 56 antibody; EC 3.4.21.- antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Serine protease 56 protein (36-116AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Serine protease required during eye development.
  • 基因功能參考文獻(xiàn)：
    1. variations in PRSS56 were evaluated in patients with either primary angle-closure glaucoma (PACG) or high hyperopia. PMID: 24227917
    2. Idenification of a founder mutation in the PRSS56 gene in Tunisian families with posterior microphthalmia and nanophthalmia. PMID: 23820083
    3. Corneal diameter decreases with decreasing axial length, suggesting posterior microphthalmos and nanophthalmos represent a spectrum of high hyperopia rather than distinct phenotypes. In the Saudi population PRSS56 mutations are the major cause. PMID: 23127749
    4. PRSS56 is a good candidate for the causal gene for nanophthalmos in a Mexican-Canadian family cohort. PMID: 21850159
    5. Together, these data suggest that alterations of this serine protease may contribute to a spectrum of human ocular conditions including reduced ocular size and ACG. PMID: 21532570
    6. Three different mutations in PRSS56, were detected in microphthalmos patients of the Faroese families. PMID: 21397065

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  • 相關(guān)疾病：
    Microphthalmia, isolated, 6 (MCOP6)
  • 蛋白家族：
    Peptidase S1 family
  • 組織特異性：
    Expressed neural retina, cornea, sclera and optic nerve.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 39433

    OMIM: 613517

    KEGG: hsa:646960

    UniGene: Hs.570310