PSD Antibody
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中文名稱:PSD兔多克隆抗體
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貨號(hào):CSB-PA018842LA01HU
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規(guī)格:¥440
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促銷:
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圖片:
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Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: PSD antibody at 3.2µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 110, 71 kDa
Observed band size: 110 kDa -
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA018842LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA018842LA01HU at dilution of 1:100
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) PSD Polyclonal antibody
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Uniprot No.:
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基因名:
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別名:PSD antibody; EFA6 antibody; EFA6A antibody; KIAA2011 antibody; PSD1 antibody; TYL antibody; PH and SEC7 domain-containing protein 1 antibody; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 antibody; Exchange factor for ARF6 antibody; Exchange factor for ARF6 A antibody; Pleckstrin homology and SEC7 domain-containing protein 1 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human PH and SEC7 domain-containing protein 1 protein (247-489AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
本頁面中的產(chǎn)品,PSD Antibody (CSB-PA018842LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于PSD Antibody,我們還提供其他標(biāo)記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, WB, IHC
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:5000 IHC 1:20-1:200 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Guanine nucleotide exchange factor for ARF6. Induces cytoskeletal remodeling.
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基因功能參考文獻(xiàn):
- Arf GTPases are likely to be locally activated by EFA6 and in turn targeted to the Flemming body to complete cytokinesis. PMID: 26330566
- PSD expression might be a useful biomarker for epigenetic-based gastric cancer early diagnosis and may lead to the identification of new targets for pharmacological intervention. PMID: 25355626
- EFA6 is regulated by a negative feedback loop, which is mediated by an allosteric interaction of Arf6-GTP with a domain of EFA6 and monitors the activation of Arf1 and Arf6 differentially PMID: 25114232
- EFA6 participates in activation of Arf6 around the cleavage furrow during cytokinesis. PMID: 23603394
- Aberrant methylation of PSD occurs in UC-associated colorectal mucosa, enabling circumvention of Rac1 immune responses governing neutrophil chemotaxis and apoptosis, and plays a pivotal role in the mechanisms underlying UC-associated carcinogenesis. PMID: 22179719
- Both levels of accumulation of F-actin and apoptosis were significantly decreased in specimens from UC patients with PSD methylation compared to those without PSD methylation. PMID: 22002136
- Pleckstrin is a critical molecule for proinflammatory cytokine secretion in response to elevated advanced glycation end products (AGE) in diabetes. PMID: 17579087
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亞細(xì)胞定位:Cell membrane. Cell projection, ruffle membrane. Cleavage furrow.
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蛋白家族:PSD family
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組織特異性:Isoform 2 is expressed in the brain.
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數(shù)據(jù)庫鏈接:
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