PTPRF Antibody, Biotin conjugated
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中文名稱:PTPRF兔多克隆抗體, Biotin偶聯(lián)
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貨號:CSB-PA019053LD01HU
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規(guī)格:¥880
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) PTPRF Polyclonal antibody
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Uniprot No.:
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基因名:
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別名:FLJ43335 antibody; FLJ45062 antibody; FLJ45567 antibody; LAR antibody; LAR protein antibody; LARFN5C antibody; LARS antibody; LCA homolog antibody; Leukocyte antigen related (LAR) PTP receptor antibody; Leukocyte antigen related antibody; Leukocyte antigen related PTP receptor antibody; Leukocyte antigen related tyrosine phosphatase antibody; Leukocyte common antigen related antibody; Protein Tyrosine Phosphatase Receptor Type F antibody; Protein tyrosine phosphatase receptor type F polypeptide antibody; Ptprf antibody; PTPRF protein antibody; PTPRF_HUMAN antibody; Receptor linked protein tyrosine phosphatase LAR antibody; Receptor type tyrosine protein phosphatase F antibody; Receptor type tyrosine protein phosphatase F precursor antibody; Receptor-type tyrosine-protein phosphatase F antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human Receptor-type tyrosine-protein phosphatase F protein (688-970AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Biotin
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA
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Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
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功能:Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity.; The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.
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基因功能參考文獻:
- transferred nuclear Overhauser effects (trNOEs) have been employed in the docking program HADDOCK to generate models for the LAR-fondaparinux complex. These models are further analyzed by postprocessing energetic analysis to identify key binding interactions. PMID: 29570275
- PTPRF may have value as a predictive marker to identify which patients can obtain the greatest benefit from erlotinib in the post-first-line setting. PMID: 26291013
- Homozygous truncating PTPRF mutation causes athelia. PMID: 24781087
- PTPRF is down-regulated in hepatocellular carcinoma-facilitated tumor development. PMID: 24470239
- Interaction between the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses. PMID: 23986473
- LAR functions as a negative regulator of adipogenesis. PMID: 19910497
- regulation of expression by cell density through functional E-cadherin complexes PMID: 12095414
- LAR PTPase domains play distinct functional roles in phosphorylation and dephosphorylation PMID: 12496362
- LAR as a crucial regulator of the sensitivity of two key insulin signalling pathways to insulin PMID: 15896785
- Results identify a protein tyrosine phosphatase as a potential substrate of TACE and describe proteolytic processing of PTP-LAR as a means of regulating phosphatase activity downstream and thus under the control of EGFR-mediated signaling pathways. PMID: 16478662
- Regulated degradation of liprinalpha1 is important for proper LAR receptor distribution, and could provide a mechanism for localized control of dendrite and synapse morphogenesis by activity and CaMKII. PMID: 17419996
- LAR and Src are identified as Death-associated protein kinase (DAPK) regulators through their reciprocal modification of DAPK Y491/492 residues and establishes a functional link of this DAPK-regulatory circuit to tumor progression. PMID: 17803936
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相關(guān)疾?。?/div>Aplasia or hypoplasia of the breasts and/or nipples 2 (BNAH2)亞細胞定位:Membrane; Single-pass type I membrane protein.蛋白家族:Protein-tyrosine phosphatase family, Receptor class 2A subfamily數(shù)據(jù)庫鏈接:
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