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RAB37 Antibody

  • 中文名稱：
    RAB37兔多克隆抗體
  • 貨號(hào)：
    CSB-PA009267
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    RAB37
  • 別名：
    B230331O03Rik antibody; B230354I04Rik antibody; FLJ30284 antibody; FLJ32507 antibody; GTPase Rab37 antibody; MGC157622 antibody; OTTMUSP00000003775 antibody; RAB 37 antibody; Rab37 antibody; Rab37 like antibody; RAB37 member RAS oncogene family antibody; RAB37_HUMAN antibody; Ras related protein Rab 37 antibody; Ras related protein Rab37 antibody; Ras-related protein Rab-37 antibody; RP23-342L24.2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human Rab 37.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. Our findings suggest that Rab37-mediated TSP1 secretion in cancer cells suppresses metastasis and angiogenesis via a cross-talk with endothelial cells and reveal a novel component of the vesicular exocytic machinery in tumor microenvironment and tumor progression PMID: 28151721
    2. Results identify Rab37 as an additional component of the machinery governing exocytosis of beta-cells and suggest that impaired expression of this GTPase may contribute to defective insulin release in pre-diabetic and diabetic conditions. PMID: 23826383
    3. RAB37 regulates the exocytosis of TIMP1 in a nucleotide-dependent manner to inactivate MMP9 migration axis in vitro and in vivo and to suppress tumor metastasis. PMID: 25183545
    4. Rab37 mRNA was specifically expressed in some ESCC cell lines but its genetic polymorphisms were not associated with esophageal squamous cell carcinoma. PMID: 23372429
    5. Promoter/exon1 methylation is the predominant mechanism in down-regulation of the hRAB37, and can serve as a potential prediction biomarker of NSCLC progression. PMID: 18687502
    6. the TMEM22/RAB37 complex is likely to play a crucial role in growth of renal cell carcinoma PMID: 19148500

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  • 亞細(xì)胞定位：
    Cytoplasmic vesicle.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 30268

    OMIM: 609956

    KEGG: hsa:326624

    STRING: 9606.ENSP00000376390

    UniGene: Hs.351413