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RASL10A Antibody

  • 中文名稱：
    RASL10A兔多克隆抗體
  • 貨號(hào)：
    CSB-PA006673
  • 規(guī)格：
    ￥880
  • 圖片：
    • Western Blot analysis of MOUSE-SPLEEN cells using RRP22 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    RASL10A
  • 別名：
    RASL10A antibody; RRP22 antibody; Ras-like protein family member 10A antibody; Ras-like protein RRP22 antibody; Ras-related protein on chromosome 22 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human RRP22.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Potent inhibitor of cellular proliferation.
  • 基因功能參考文獻(xiàn)：
    1. RRP22 is a special neural tumor suppressor for human astrocytomas PMID: 21264544
    2. Both 5'-CpG island hypermethylation and histone modifications contribute to the frequent and prognostically unfavorable transcriptional downregulation of RRP22 in malignant gliomas. PMID: 21631628
    3. chromosome 22 have specific motor deficits in axial stability and graphomotor skills. PMID: 20646714
    4. RRP22 localizes to the nucleolus in a GTP-dependent manner and can serve as a potential tumor suppressor. PMID: 15833841
  • 亞細(xì)胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side. Nucleus, nucleolus. Note=May cycle in and out of the nucleolus in a GTP-dependent manner.
  • 蛋白家族：
    Small GTPase superfamily, Ras family
  • 組織特異性：
    Expression appears to be strictly limited to the central nervous system.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16954

    OMIM: 602220

    KEGG: hsa:10633

    STRING: 9606.ENSP00000216101

    UniGene: Hs.73088