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RASSF3 Antibody, Biotin conjugated

  • 中文名稱：
    RASSF3兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA801247LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RASSF3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RASSF3
  • 別名：
    MGC119194 antibody; MGC119195 antibody; MGC119197 antibody; Ras association (RalGDS/AF 6) domain family 3 antibody; Ras association domain containing protein 3 antibody; Ras association domain-containing protein 3 antibody; RASF3_HUMAN antibody; Rassf3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Ras association domain-containing protein 3 protein (2-109AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. low expression is associated with malignant phenotypes in non-small cell lung cancer patients PMID: 24246507
    2. Taken together, these findings indicate that the RASSF3 promoter rs6581580 T>G SNP is potentially functional, modulating susceptibility to SCCHN among non-Hispanic whites. PMID: 24295637
    3. hypermethylation-induced RASSF3 silencing plays an important role in the tumorigenesis of pituitary somatotroph adenomas. PMID: 23555615
    4. tumor suppressor activity of RASSF3, which occurs through p53 stabilization and regulation of apoptosis and the cell cycle. PMID: 22593196
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 20237496
    6. Mammary tumor incidence in bi-transgenic mice is delayed, suggesting that transgenic Rassf3 may influence mammary tumor incidence in transgenic mice PMID: 19148488
    7. The presence of a Ras association domain common to NORE1,RASSF1, and RASSF3 suggests their possible involvement inRas-like signaling pathways. PMID: 11965544

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  • 亞細(xì)胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Note=Localized to microtubules in vascular endothelial cells.
  • 組織特異性：
    Widely expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 14271

    OMIM: 607019

    KEGG: hsa:283349

    STRING: 9606.ENSP00000336616

    UniGene: Hs.643605