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RASSF4 Antibody, Biotin conjugated

  • 中文名稱:
    RASSF4兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA880956LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) RASSF4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RASSF4
  • 別名:
    3830411C14Rik antibody; AD037 antibody; AI586137 antibody; MGC105606 antibody; MGC44914 antibody; OTTHUMP00000019493 antibody; Ras association (RalGDS/AF 6) domain family 4 antibody; Ras association (RalGDS/AF 6) domain family member 4 antibody; Ras association domain containing protein 4 antibody; Ras association domain family 4 antibody; Ras association domain-containing protein 4 antibody; RASF4_HUMAN antibody; RASSF 4 antibody; Rassf4 antibody; RP11-285G1.4 antibody; Tumor suppressor RASSF4 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Ras association domain-containing protein 4 protein (65-180AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
  • 基因功能參考文獻(xiàn):
    1. RASSF4 controls store operated calcium entry and endoplasmic reticulum-plasma membrane junctions through ARF6-dependent regulation of PM PI(4,5)P2 levels, pivotal for a variety of physiological processes. PMID: 28600435
    2. RASSF4 overexpression inhibits proliferation, invasion, EMT, and Wnt signaling pathway in osteosarcoma cells. PMID: 28081736
    3. the present study suggested that RASSF4 serves as an important tumor suppressor in human nonsmall cell lung cancer . PMID: 26526576
    4. RASSF4 promotes EV71 replication and the production of viral progeny to accelerate the inhibition of the phosphorylation of AKT. PMID: 25701784
    5. expression of SPRR1B is upregulated in oral CSCs/CICs and SPRR1B has a role in cell growth by suppression of RASSF4 PMID: 23954638
    6. Single nucleotide polymorphism in RASSF4 gene is associated with acute lymphoblastic leukemia. PMID: 19066393

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  • 組織特異性:
    Widely expressed. Frequently down-regulated in tumor cell lines.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 20793

    OMIM: 610559

    KEGG: hsa:83937

    STRING: 9606.ENSP00000339692

    UniGene: Hs.522895