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RDH11 Antibody

  • 中文名稱：
    RDH11兔多克隆抗體
  • 貨號(hào)：
    CSB-PA019523GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    RDH11
  • 別名：
    Androgen regulated short chain dehydrogenase/reductase 1 antibody; Androgen-regulated short-chain dehydrogenase/reductase 1 antibody; ARSDR1 antibody; AU045252 antibody; C85936 antibody; CGI 82 antibody; FLJ32633 antibody; HCBP12 antibody; HCV core binding protein antibody; HCV core binding protein HCBP12 antibody; HCV core-binding protein HCBP12 antibody; MDT1 antibody; Prostate short chain dehydrogenase/reductase 1 antibody; Prostate short-chain dehydrogenase/reductase 1 antibody; PSDR1 antibody; RALR1 antibody; RDH11 antibody; RDH11_HUMAN antibody; Retinal reductase 1 antibody; retinol dehydrogenase 11 (all trans/9 cis/11 cis) antibody; Retinol dehydrogenase 11 antibody; SCALD antibody; SDR7C1 antibody; Short chain dehydrogenase/reductase family 7C; member 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human RDH11
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol. Exhibits a low reductive activity towards unsaturated medium-chain aldehydes such as cis -6-nonenal and no activity toward nonanal or 4-hydroxy-nonenal. Has no dehydrogenase activity towards steroid.
  • 基因功能參考文獻(xiàn)：
    1. Data suggest that membrane anchoring of retinol dehydrogenase 11 (RDH11) is likely driven by its N-terminal segment. PMID: 25542782
    2. Data indicate that ribosomal protein L11 (RPL11)-expressing cells proliferated more rapidly than the ribosomal protein L11 (RPL11)-expressing cells. PMID: 25829192
    3. deleterious mutations in RDH11, an important enzyme for vision-related and systemic retinoic acid metabolism, cause a new syndrome with RP. PMID: 24916380
    4. Prostate short-chain dehydrogenase/reductase (PSDR1) encodes a novel retinal reductase (RalR1). PMID: 12036956
    5. The core protein of HCV can interact with translin protein. This can partly explain the molecular mechanism for hepatocellular carcinoma and lymphoma caused by HCV. PMID: 12532453
    6. Expression pattern and high catalytic efficiency of RalR1 are consistent with the hypothesis that RalR1 contributes to the reduction of retinal in various human tissues. PMID: 14674758
    7. RDH11 localizes to photoreceptor inner segments [review] PMID: 17249616

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  • 相關(guān)疾?。?/div>
    Retinal dystrophy, juvenile cataracts, and short stature syndrome (RDJCSS)
  • 亞細(xì)胞定位：
    Endoplasmic reticulum membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family
  • 組織特異性：
    Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and f
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 17964

    OMIM: 607849

    KEGG: hsa:51109

    STRING: 9606.ENSP00000370750

    UniGene: Hs.719925