RDM1 Antibody
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中文名稱:RDM1兔多克隆抗體
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貨號(hào):CSB-PA779905
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規(guī)格:¥2024
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圖片:
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) RDM1 Polyclonal antibody
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Uniprot No.:
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基因名:RDM1
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Synthesized peptide derived from internal of Human RDM1.
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免疫原種屬:Homo sapiens (Human)
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克隆類型:Polyclonal
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純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度:It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA,IHC
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推薦稀釋比:
Application Recommended Dilution IHC 1:50-1:100 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA.
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基因功能參考文獻(xiàn):
- Due to its similarity to RAD52, we hypothesized that RDM1 potentially repairs DNA doublestrand breaks arising through DNA replication. PMID: 29845285
- RDM1 recognizes DNA distortions induced by cisplatin-DNA adducts in vitro; possible role in spermatogenesis PMID: 15611051
- The identification of 11 human cDNAs encoding RDM1 protein isoforms which is generated by alternative pre-mRNA splicing and differential usage of two translational start sites. PMID: 17905820
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亞細(xì)胞定位:Nucleus. Cytoplasm. Nucleus, nucleolus. Note=Isoform 3 and isoform 10 are predominantly nuclear and nucleolar. After treatment with proteasomal inhibitors and mild heat-shock stress, isoform 1, isoform 3, isoform 5, isoform 7, isoform 8 and isoform 10 are relocalized to the nucleolus as dot-like or irregular subnuclear structures. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress. Isoform 3, but not isoform 1 and isoform 5, is relocalized in nucleolar caps during transcriptional arrest.; [Isoform 1]: Cytoplasm. Nucleus, PML body. Nucleus, Cajal body. Note=Isoform 1 is predominantly cytoplasmic. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress.
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組織特異性:Expressed in testis.
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數(shù)據(jù)庫鏈接:
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