RGS12 Antibody
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中文名稱:RGS12兔多克隆抗體
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貨號:CSB-PA694009
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規(guī)格:¥2024
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圖片:
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) RGS12 Polyclonal antibody
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Uniprot No.:
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基因名:RGS12
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Synthesized peptide derived from N-terminal of Human RGS12.
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免疫原種屬:Homo sapiens (Human)
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克隆類型:Polyclonal
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純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度:It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA,WB
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:3000 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.; Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis.
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基因功能參考文獻(xiàn):
- Findings identify RGS12 as a candidate tumor-suppressor gene in AA prostate cancer, which acts by decreasing expression of AKT and MNX1, establishing a novel oncogenic axis in this disparate disease setting. PMID: 28611045
- Data support the notion that the Galpha, but not Gbetagamma, arm of the Gi/o signalling is involved in TRPC4 activation and unveil new roles for RGS and RGS12 in fine-tuning TRPC4 activities. PMID: 26987813
- RGS12 is essential for the terminal differentiation of osteoclasts induced by RANKL. PMID: 17042716
- shows chromosomal mapping information for human locus. PMID: 9168931
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亞細(xì)胞定位:Nucleus. Cytoplasm. Cell projection, dendrite. Cell junction, synapse.; [Isoform 5]: Nucleus matrix.
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組織特異性:Isoform 3 is brain specific.
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數(shù)據(jù)庫鏈接:
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