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RGS13 Antibody

  • 中文名稱：
    RGS13兔多克隆抗體
  • 貨號：
    CSB-PA019645GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    RGS13
  • 別名：
    AL713991.1 antibody; HGNC:9995 antibody; MGC17173 antibody; OTTMUSP00000022853 antibody; OTTMUSP00000022854 antibody; Regulator of G protein signalling 13 antibody; Regulator of G-protein signaling 13 antibody; RGD1562103 antibody; RGS 13 antibody; RGS13 antibody; RGS13_HUMAN antibody; RP11 92K2.1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human RGS13
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)-alpha.
  • 基因功能參考文獻(xiàn)：
    1. p53 may modulate immune responses through suppression of RGS13 transcription in mast cells and B cells PMID: 21531726
    2. RGS13 turnover was significantly reduced in cells stimulated with cAMP, which was reversed by expression of the PKA-specific inhibitory peptide PKI. PMID: 20974683
    3. Functional characterization of the G protein regulator RGS13 PMID: 11875076
    4. Down-Regulation of regulator of G-protein signalling 13 is associated with mantle cell lymphoma PMID: 12970790
    5. RGS13 overexpression inhibited CXCL12-evoked Ca(2+) mobilization, Akt phosphorylation and chemotaxis. PMID: 19017978

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  • 數(shù)據(jù)庫鏈接：

    HGNC: 9995

    OMIM: 607190

    KEGG: hsa:6003

    STRING: 9606.ENSP00000375853

    UniGene: Hs.497220