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RIMS2 Antibody, HRP conjugated

  • 中文名稱：
    RIMS2兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA892173LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RIMS2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RIMS2
  • 別名：
    KIAA0751 antibody; Non small cell lung cancer RimL3a protein antibody; Non small cell lung cancer RimL3c protein antibody; OBOE antibody; Protein regulating synaptic membrane exocytosis 2 antibody; Rab-3-interacting molecule 2 antibody; Rab-3-interacting protein 3 antibody; Rab3 interacting molecule 2 antibody; RAB3IP3 antibody; Regulating synaptic membrane exocytosis 2 antibody; Regulating synaptic membrane exocytosis protein 2 antibody; RIM 2 antibody; Rims2 (gene name) antibody; Rims2 antibody; RIMS2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Regulating synaptic membrane exocytosis protein 2 protein (667-943AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes.
  • 基因功能參考文獻：
    1. Electrophysiological characterization of VDCC currents revealed that the suppressive effect of RIM2alpha on voltage-dependent inactivation (VDI) was stronger than that of RIM1alpha for the CaV2.1 variant containing the region encoded by exons 44 and 47. PMID: 28377503
    2. Here, we report that, like Rab3A, RIM and Munc13 are present in human sperm and that they play a functional role in acrosomal exocytosis before the acrosomal calcium efflux PMID: 22248876
    3. These data suggest that RIM2beta contributes to the stabilization of Ca(v)1.3 gating kinetics in immature cochlear inner hair cells. PMID: 20363327
    4. Western blot analysis shows increased RIMS2 protein expression in the amygdala in schizophrenia. PMID: 18490030
    5. tick-borne encephalitis virus -NS5 has high affinity to regulating synaptic membrane exocytosis-2 (RIMS2) and Scribble, whereas DENV-NS5 binds primarily to the tight junction protein zonula occludens-1 (ZO-1) PMID: 19199833

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  • 亞細胞定位：
    Cell membrane; Peripheral membrane protein. Cell junction, synapse. Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein.
  • 組織特異性：
    Widely expressed. Expressed in melanocytes. In fetal tissues, predominantly expressed in the brain. In the retina, expressed in the outer plexiform layer (at protein level). In the cerebellum, expressed in Purkinje cells (at protein level). In the pancrea
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17283

    OMIM: 606630

    KEGG: hsa:9699

    UniGene: Hs.655271