RIN3 Antibody
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中文名稱:RIN3兔多克隆抗體
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貨號:CSB-PA019728LA01HU
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規(guī)格:¥440
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促銷:
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圖片:
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Immunofluorescence staining of Hela cells with CSB-PA019728LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) RIN3 Polyclonal antibody
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Uniprot No.:
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基因名:RIN3
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別名:RIN3 antibody; Ras and Rab interactor 3 antibody; Ras interaction/interference protein 3 antibody
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宿主:Rabbit
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反應種屬:Human
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免疫原:Recombinant Human Ras and Rab interactor 3 protein (245-465AA)
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免疫原種屬:Homo sapiens (Human)
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標記方式:Non-conjugated
本頁面中的產(chǎn)品,RIN3 Antibody (CSB-PA019728LA01HU),的標記方式是Non-conjugated。對于RIN3 Antibody,我們還提供其他標記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應用范圍:ELISA, IF
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推薦稀釋比:
Application Recommended Dilution IF 1:50-1:200 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
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功能:Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function.
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基因功能參考文獻:
- RIN3 may be involved in endolysosomal transport-a process known to be important to development of early onset AD. PMID: 28738127
- RIN3 may contribute to Paget's disease of bone susceptibility by affecting osteoclast function. PMID: 25701875
- discovered novel interaction candidates for CD2AP and characterized subtle yet significant differences in the recognition preferences of its three SH3 domains for c-CBL, ALIX, and RIN3 PMID: 26296892
- The study reports a novel association between a variant within RIN3 and lower limb-bone mineral density and note its previous association with risk of Paget's disease. PMID: 24945404
- RIN3 is a negative regulator of mast cell responses to SCF PMID: 23185384
- RIN3 specifically acts as a GEF for Rab31. PMID: 21586568
- RIN3 biochemically characterized as the stimulator and stabilizer for GTP-Rab5 plays an important role in the transport pathway from plasma membrane to early endosomes PMID: 12972505
- Tyrosine-phosphorylation signals are involved in the RIN3 activation and translocation to early endocytic vesicles. PMID: 18486601
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亞細胞定位:Cytoplasm. Cytoplasmic vesicle. Early endosome.
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蛋白家族:RIN (Ras interaction/interference) family
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組織特異性:Widely expressed.
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數(shù)據(jù)庫鏈接:
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