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RPLP2 Antibody

  • 中文名稱：
    RPLP2兔多克隆抗體
  • 貨號：
    CSB-PA020342DSR1HU
  • 規(guī)格：
    ￥440
  • 促銷：
    小規(guī)格抗體限時一口價
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA020342DSR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA020342DSR1HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RPLP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RPLP2
  • 別名：
    2700049I22Rik antibody; 60S acidic ribosomal protein P2 antibody; Acidic ribosomal phosphoprotein P2 antibody; D11S2243E antibody; LP2 antibody; MGC71408 antibody; OTTMUSP00000029428 antibody; OTTMUSP00000029429 antibody; OTTMUSP00000029430 antibody; P2 antibody; Renal carcinoma antigen NY-REN-44 antibody; Ribosomal protein P2 antibody; Ribosomal protein, large, P2 antibody; RLA2_HUMAN antibody; rplP2 antibody; RPP2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human 60S acidic ribosomal protein P2 protein (1-115AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays an important role in the elongation step of protein synthesis.
  • 基因功能參考文獻：
    1. Collectively, the present results suggest that PhoRpp21 binds the loop between P11 and P12 helices through overall positively charged clusters on the surface of the complex and serves as a scaffold for PhoRpp29 to optimize structural conformation of its N-terminal helix (alpha2) in PhoRpp21, as well as C-terminal residues in PhoRpp29, for RNase P activity. PMID: 27810361
    2. Results show that the conserved C-terminal segment of P2 from three different eukaryotic species- Human, Plasmodium falciparum and Toxoplasma gondii is intrinsically disordered. PMID: 25412900
    3. relevance of the observed cross-reactive IgE autoantibodies against P2 proteins in systemic lupus eryth remains to be elucidated PMID: 21410706
    4. the eukaryotic stalk protein P2 forms a symmetric homodimer in solution, and is structurally distinct from the bacterial counterpart L12 homodimer. PMID: 20385603
    5. Ribosomal protein P2 has been identified as a novel substrate of GRK2 in HEK-293 cells where P2 phosphorylation is increased following agonist stimulation of the beta 2-adrenergic receptor under conditions of tyrosine kinase PKC and PKA inhibition. PMID: 12379128
    6. Antisense-mediated depletion may disrupt the proteome of cancer cells. PMID: 14981896
    7. Distinct roles for CD39 and P2-purinergic signaling in both tissue remodeling and fibrogenesis with respect to human pancreatic diseases. PMID: 16920697

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  • 蛋白家族：
    Eukaryotic ribosomal protein P1/P2 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10377

    OMIM: 180530

    KEGG: hsa:6181

    STRING: 9606.ENSP00000322419

    UniGene: Hs.437594