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SCN7A Antibody

  • 中文名稱:
    SCN7A兔多克隆抗體
  • 貨號:
    CSB-PA779166
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Immunofluorescence analysis of A549 cells, using SCN7A antibody.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) SCN7A Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SCN7A
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human SCN7A.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:100-1:500
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能:
    Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
  • 基因功能參考文獻:
    1. The authors demonstrated that the sodium channel Nax functions as a sodium sensor. With increased extracellular sodium, Nax up-regulates prostasin, which results in activation of the sodium channel ENaC. PMID: 26537257
    2. SNP rs7565062 of SCN7A was significantly associated with essential hypertension in a Northern Han Chinese population PMID: 25393565
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Sodium channel (TC 1.A.1.10) family, SCN7A subfamily
  • 組織特異性:
    Heart and uterus.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 10594

    OMIM: 182392

    KEGG: hsa:6332

    STRING: 9606.ENSP00000386796

    UniGene: Hs.596087