SLC30A3 Antibody, Biotin conjugated
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中文名稱:SLC30A3兔多克隆抗體, Biotin偶聯(lián)
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貨號(hào):CSB-PA859940LD01HU
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規(guī)格:¥880
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) SLC30A3 Polyclonal antibody
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Uniprot No.:
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基因名:SLC30A3
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別名:SLC30A3; ZNT3; Zinc transporter 3; ZnT-3; Solute carrier family 30 member 3
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human Zinc transporter 3 protein (286-388AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Biotin
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA
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Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Involved in accumulation of zinc in synaptic vesicles.
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基因功能參考文獻(xiàn):
- ZNT3 was only detected in human beta-cells, but not in mouse beta-cells. PMID: 29372370
- SNPs in the SLC30A3 gene and adjacent region are associated with schizophrenia in female but not male cases. PMID: 27750116
- There was a significant decreased in protein levels of ZnT3 in the prefrontal cortex in Major depression disorder, relative to control subjects. PMID: 27661418
- The level of ERK1/2 phosphorylation was significantly increased by tunicamycin treatment in control cells, not in SLC30A3 knockdown cells. The ERK1/2 pathway is thought to have an association with defensive effects of SLC30A3 on cellular stress such as ER stress. PMID: 27678294
- ZNT3 and ZNT8 (known to regulate insulin secretion) have opposite effects on insulin synthesis and secretion possibly by a transcriptional co-regulation since mRNA expression of ZNT3 was inversely correlated to ZNT8 and ZNT3 over-expression reduced insulin synthesis and secretion. PMID: 26867900
- An association was found between reduced ZnT3 in the prefrontal cortex and cognitive impairment in patients with either dementia with Lewy bodies or Parkinson's disease dementia. PMID: 25104558
- SNPs in SLC30A3 show a gender-specific association with schizophrenia in an East UK cohort. PMID: 23849395
- this study provides the first evidence of a role for zinc in depression in people with dementia. PMID: 24953873
- The results of this study suggested that ZnT3 protein levels are decreased in the spinal cords of sporadic ALS patients. PMID: 25284286
- hZnT-3 is expressed at low levels in leukocytes. PMID: 17971500
- Data show that ZNT3 is extensively present in the Abeta-positive plaques in the cortex of human AD brains. PMID: 18639746
- SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity PMID: 19521526
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亞細(xì)胞定位:Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome. Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
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蛋白家族:Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
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數(shù)據(jù)庫(kù)鏈接:
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