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SLC39A9 Antibody

  • 中文名稱(chēng)：
    SLC39A9兔多克隆抗體
  • 貨號(hào)：
    CSB-PA233395
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/20.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) SLC39A9 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SLC39A9
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide corresponding to a region derived from internal residues of Human solute carrier family 39, member 9
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類(lèi)型：
    Polyclonal
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:50-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May act as a zinc-influx transporter.
  • 基因功能參考文獻(xiàn)：
    1. The study connects structural features of ZIP9 to its functions and indicates a possible relevance of ZIP9 as a pharmacological target PMID: 28943399
    2. ZIP9 role glioblastoma cells migration.ZIP9 expression affects phosphorylation states of p53 and GSK-3beta. PMID: 27654922
    3. The results show ZIP9 is a specific Gi coupled-mAR mediating testosterone-induced MAP kinase and zinc signaling in PC3-ZIP9 cells. PMID: 28219737
    4. ZIP9 expression in glioma tumors was not associated with tumor grade or IDH1 mutation status. PMID: 25921144
    5. ZIP9 mediates testosterone promotion of apoptosis and is widely expressed in human tissues and up-regulated in malignant breast and prostate tissues, suggesting that it is a potential therapeutic target for treating breast and prostate cancers. PMID: 25014355
    6. SLC39A9 functions to regulate zinc homeostasis in the secretory pathway without significantly altering cytosolic zinc homeostasis. PMID: 19420709

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  • 亞細(xì)胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ZIP transporter (TC 2.A.5) family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 20182

    KEGG: hsa:55334

    STRING: 9606.ENSP00000336887

    UniGene: Hs.432690