SLC6A12 Antibody
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中文名稱:SLC6A12兔多克隆抗體
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貨號:CSB-PA021690ESR1HU
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規(guī)格:¥440
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促銷:
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圖片:
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Western blot
All lanes: SLC6A12 antibody at 4.47µg/ml + PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 70 kDa
Observed band size: 70 kDa -
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA021690ESR1HU at dilution of 1:100
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) SLC6A12 Polyclonal antibody
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Uniprot No.:
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基因名:SLC6A12
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別名:Betaine/GABA transporter 1 antibody; BGT-1 antibody; BGT1 antibody; Gamma aminobutyric acid transporter antibody; GAT2 antibody; Na(+)/Cl(-) betaine/GABA transporter antibody; S6A12_HUMAN antibody; Slc6a12 antibody; Sodium- and chloride-dependent betaine transporter antibody; Solute carrier family 6 (neurotransmitter transporter), member 12 antibody; Solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 antibody; Solute carrier family 6 member 12 antibody
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宿主:Rabbit
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反應種屬:Human
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免疫原:Recombinant Human Sodium- and chloride-dependent betaine transporter protein (515-614AA)
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免疫原種屬:Homo sapiens (Human)
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標記方式:Non-conjugated
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:Antigen Affinity Purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式:Liquid
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應用范圍:ELISA, WB, IHC
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推薦稀釋比:
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
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功能:Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
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基因功能參考文獻:
- The SLC6A12 expression levels in peripheral blood mononuclear cells were significantly higher in TLE patients. PMID: 26690518
- T40 may be important for the trafficking and insertion of BGT1 in the plasma membrane PMID: 24829506
- JAK2 is a novel regulator of the GABA transporter BGT1. PMID: 22405821
- This study found that rs216250 of SLC6A12 was correlated with the Scale for the Assessment of Negative Symptoms (SANS) scores. PMID: 21367462
- Results showed that two polymorphisms and a haplotype in SLC6A12, were significantly associated with AIA after multiple testing corrections. PMID: 20597903
- The primary structure of BGT-1 predicts two putative phosphorylation sites for the Ca2+/diacylglycerol-dependent protein kinase (PKC), which regulates BGT-1 function by phosphorylation events in a transport system expressed in cultured astrocytoma cells. PMID: 12111824
- BGT-1 is expressed from mRNA and transports GABA in platelets. PMID: 16198020
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亞細胞定位:Membrane; Multi-pass membrane protein.
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蛋白家族:Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A12 subfamily
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組織特異性:Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.
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數(shù)據(jù)庫鏈接:
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