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SLIT1 Antibody

  • 中文名稱：
    SLIT1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA258249
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA258249(SLIT1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA258249(SLIT1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SLIT1
  • 別名：
    KIAA0813 antibody; MEGF 4 antibody; MEGF4 antibody; MGC164811 antibody; Multiple EGF-like domains protein 4 antibody; Multiple epidermal growth factor like domains 4 antibody; Multiple epidermal growth factor-like domains protein 4 antibody; OTTHUMP00000059392 antibody; SLIL 1 antibody; SLIL1 antibody; Slit 1 antibody; SLIT 3 antibody; Slit homolog 1 antibody; Slit homolog 1 protein antibody; Slit-1 antibody; Slit1 antibody; SLIT1_HUMAN antibody; SLIT3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human SLIT1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
  • 基因功能參考文獻(xiàn)：
    1. Analysis of alternative splicing and conserved domains in human and mouse slit genes PMID: 12141424
    2. evidence showing that Slit1 and Slit2 proteins are selective inhibitors and repellents for dorsally projecting, but not for ventrally projecting, cranial motor axons PMID: 16162649
    3. In fetal and embryonic stem cell cultures Slit-1 inhibited neurite outgrowth. PMID: 16840550
  • 亞細(xì)胞定位：
    Secreted.
  • 組織特異性：
    Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11085

    OMIM: 603742

    KEGG: hsa:6585

    STRING: 9606.ENSP00000266058

    UniGene: Hs.632082