SORBS3 Antibody
-
中文名稱:SORBS3兔多克隆抗體
-
貨號:CSB-PA022406LA01HU
-
規(guī)格:¥440
-
促銷:
-
圖片:
-
Western blot
All lanes: SORBS3 antibody at 8µg/ml + HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 76, 37 kDa
Observed band size: 76 kDa -
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA022406LA01HU at dilution of 1:100
-
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA022406LA01HU at dilution of 1:100
-
-
其他:
產(chǎn)品詳情
-
產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) SORBS3 Polyclonal antibody
-
Uniprot No.:
-
基因名:SORBS3
-
別名:SORBS3 antibody; SCAM1 antibody; Vinexin antibody; SH3-containing adapter molecule 1 antibody; SCAM-1 antibody; Sorbin and SH3 domain-containing protein 3 antibody
-
宿主:Rabbit
-
反應(yīng)種屬:Human
-
免疫原:Recombinant Human Vinexin protein (1-329AA)
-
免疫原種屬:Homo sapiens (Human)
-
標(biāo)記方式:Non-conjugated
本頁面中的產(chǎn)品,SORBS3 Antibody (CSB-PA022406LA01HU),的標(biāo)記方式是Non-conjugated。對于SORBS3 Antibody,我們還提供其他標(biāo)記。見下表:
-
克隆類型:Polyclonal
-
抗體亞型:IgG
-
純化方式:>95%, Protein G purified
-
濃度:It differs from different batches. Please contact us to confirm it.
-
保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
-
應(yīng)用范圍:ELISA, WB, IHC
-
推薦稀釋比:
Application Recommended Dilution WB 1:500-1:2000 IHC 1:20-1:200 -
Protocols:
-
儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
-
功能:Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain.
-
基因功能參考文獻:
- Vinexin beta deficiency attenuates atherogenesis primarily by suppressing vascular inflammation and inactivating Akt-nuclear factor kappaB signaling. Our data suggest that vinexin beta could be a therapeutic target for the treatment of atherosclerosis. PMID: 28209562
- The chromosome 8p tumor suppressor genes SORBS3 and SH2D4A are physically and functionally linked and provide a molecular mechanism of inhibiting STAT3-mediated IL-6 signaling in hepatocellular carcinoma cells. PMID: 27311882
- Study identified possible epigenetic influence on differential gene expression in SORBS3 under obese conditions. PMID: 27437034
- Our findings revealed that Vinexin-beta acts as a novel modulator of ischaemic injury PMID: 25824575
- Taken together, the findings suggest that vinexin beta modulates NS5A phosphorylation via its interaction with NS5A, thereby regulating hepatitis C virus replication, implicating vinexin beta in the viral life cycle. PMID: 25972535
- Vinexin knockdown using siRNA delayed migration of both HaCaT human keratinocytes and A431 epidermoid carcinoma cells in scratch assay but did not affect cell proliferation. PMID: 20361963
- regulates cytoskeletal organization and signal transduction--review PMID: 12510380
- vinexin is a novel substrate of ERK2 and may play roles in ERK-dependent cell regulation PMID: 15184391
- phosphorylation of the AF-1 domain controls RARgamma-mediated transcription through triggering the dissociation of vinexin beta PMID: 15734736
- These results suggest that vinexin beta plays a role in maintaining the phosphorylation of EGFR on the plasma membrane through the regulation of c-Cbl. PMID: 16923119
- Vinexin is enriched at the leading edge of migrating cells, lamellipodia and and focal adhesions in well-spread cells. PMID: 17486060
- Rhotekin forms a complex with vinexin and may play a role at focal adhesions. PMID: 19294487
顯示更多
收起更多
-
亞細(xì)胞定位:[Isoform Alpha]: Cell junction. Cytoplasm, cytoskeleton.; [Isoform Beta]: Cell junction. Nucleus. Cytoplasm, cytoskeleton.
-
組織特異性:Both isoforms are expressed in different tissues like heart, placenta, brain, skeletal muscle and pancreas. Isoform beta is especially found in liver.
-
數(shù)據(jù)庫鏈接:
Most popular with customers
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-