SOS2 Antibody
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中文名稱:SOS2兔多克隆抗體
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貨號(hào):CSB-PA050119
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規(guī)格:¥880
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:
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別名:FLJ25596 antibody; Guanine nucleotide exchange factor antibody; Guanine nucleotide releasing factor antibody; Son of sevenless (Drosophilia) homolog 2 antibody; Son of sevenless homolog 2 (Drosophila) antibody; Son of sevenless homolog 2 antibody; SOS 2 antibody; SOS-2 antibody; Sos2 antibody; SOS2_HUMAN antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Synthesized peptide derived from the Internal region of Human Sos 2.
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:WB, ELISA
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:10000 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Promotes the exchange of Ras-bound GDP by GTP.
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基因功能參考文獻(xiàn):
- Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome PMID: 26173643
- We identified two novel genes, SOS2 and LZTR1, associated with Noonan syndrome, thereby expanding the molecular spectrum of RASopathies. PMID: 25795793
- multicenter pharmacogenetic study in children (ages 6-11): Data suggest that SNP in SOS2 (rs13379306) in children with growth hormone deficiency is associated with drug resistance to hormone replacement therapy with recombinant human growth hormone. PMID: 23761422
- intracellular Francisella tularensis novicida triggers temporal and early activation of Ras through the SOS2/GrB2/PKCalpha/PKCbetaI quaternary complex; Ras signalling by intracellular F. tularensis is essential for intracellular proliferation in the cytosol PMID: 20618341
- Significant association of single nucleotide polymorphism within three genes--PPARgamma, SOS2, and PCK1--with Alzheimer's disease, was confirmed. PMID: 17440948
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相關(guān)疾病:Noonan syndrome 9 (NS9)
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數(shù)據(jù)庫(kù)鏈接:
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