SPY Antibody
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中文名稱:SPY兔多克隆抗體
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貨號(hào):CSB-PA300608XA01ENV
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規(guī)格:¥440
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促銷:
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圖片:
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:SPY
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別名:Periplasmic chaperone Spy (Spheroplast protein Y) spy b1743 JW1732
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反應(yīng)種屬:Escherichia coli (strain K12)
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免疫原:Recombinant Escherichia coli (strain K12) SPY protein (52-147aa)
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免疫原種屬:Escherichia coli (strain K12)
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標(biāo)記方式:Non-conjugated
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:Protein G
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, WB
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Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:An ATP-independent periplasmic chaperone, decreases protein aggregation and helps protein refolding. Binds substrate over a large region of its convex inner surface. Substrate protein folds while it is bound to chaperone. Increasing Spy flexibility increases its substrate affinity and overall chaperone activity (shown for 3 different substrates). Protects proteins in vitro against tannin inactivation; tannins have antimicrobial activity. Overexpression enhances the stability of otherwise unstable periplasmic proteins.
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基因功能參考文獻(xiàn):
- Visualizing of Spy chaperone-assisted Im7 protein folding has been reported. PMID: 27239796
- Experimental results on Spy-Im7 interactions were used to construct a model for how this chaperone interacts with its clients. It appears that Spy binds to and releases client proteins in a regulated fashion that uses client protein folding as its own cue for release. PMID: 27293188
- Spy rapidly associates with its substrate, immunity protein 7 (Im7), thereby eliminating Im7's potential for aggregation. PMID: 26619265
- Establish a good relationship between the degree of instability and the improvement chaperone activity of spy variants. PMID: 24497545
- Report of the crystal structure of Escherichia coli spheroplast protein y (EcSpy). PMID: 20799348
- The induction of spy gene transcription by external zinc may include multiple steps such as through sensing the zinc-induced envelope disorder by BaeSR. PMID: 17884222
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亞細(xì)胞定位:Periplasm.
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蛋白家族:CpxP/Spy family
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數(shù)據(jù)庫(kù)鏈接:
KEGG: ecj:JW1732
STRING: 316385.ECDH10B_1881
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