ST18 Antibody
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中文名稱:ST18兔多克隆抗體
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貨號:CSB-PA575960
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規(guī)格:¥1100
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圖片:
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:ST18
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別名:KIAA0535 antibody; St18 antibody; ST18_HUMAN antibody; suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein) antibody; Suppression of tumorigenicity 18 protein antibody; Suppression of tumorigenicity protein 18 antibody; Zinc finger protein 387 antibody; Znf387 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human,Mouse,Rat
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免疫原:Fusion protein of Human ST18
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:Antigen affinity purification
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA,IHC
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推薦稀釋比:
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:25-1:100 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters. Inhibits colony formation in cultured breast cancer cells.
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基因功能參考文獻(xiàn):
- the present findings indicate that ST18 may play a direct role in Pemphigus vulgaris (PV) and consequently represents a potential target for the treatment of this disease. PMID: 27148741
- ST18 expression and activity are increased in cytotoxic conditions in pancreatic beta-cells. Overexpression of ST18 causes apoptosis. PMID: 24509857
- In our study, rs1015213 (located in the intergenic region between PCMTD1 and ST18) was associated significantly with primary angle closure. PMID: 23847314
- Presence of at least one A allele (AG or AA genotype) for rs1015213 was associated with a shallower anterior chamber depth (-0.07 mm, 95% CI -0.01 to -0.14 mm, p=0.028) after adjusting for age and sex (both p=0.001). PMID: 23505305
- a significant association between ST18 and predisposition to Pemphigus vulgaris (PV). PMID: 22437316
- ectopic ST18 expression in MCF-7 breast cancer cells strongly inhibits colony formation in soft agar and the formation of tumors in a xenograft mouse model PMID: 15489893
- Fibroblasts that overexpress ST18 by transient transfection exhibit significantly increased apoptosis and increased expression of TNF-alpha, interleukin (IL) -1alpha, and IL-6. PMID: 18676404
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亞細(xì)胞定位:Nucleus.
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蛋白家族:MYT1 family
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組織特異性:Detected at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells.
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