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ST6GALNAC1 Antibody

  • 中文名稱：
    ST6GALNAC1兔多克隆抗體
  • 貨號：
    CSB-PA868312LA01HU
  • 規(guī)格：
    ￥440
  • 促銷：
    小規(guī)格抗體限時一口價
  • 圖片：
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate
      All lanes: ST6GALNAC1 antibody at 2.7μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 69 kDa
      Observed band size: 69 kDa
    • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA868312LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA868312LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ST6GALNAC1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ST6GALNAC1
  • 別名：
    6-sialyltransferase 1 antibody; 6-sialyltransferase I antibody; Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase 1 antibody; Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase antibody; Alpha-N-acetylgalactosaminide alpha-2 antibody; GalNAc alpha 2 6 sialyltransferase I antibody; GalNAc alpha-2 antibody; HSY11339 antibody; SIA7A_HUMAN antibody; Sialyltransferase 7A antibody; SIAT7-A antibody; SIAT7A antibody; ST6 (alpha N acetyl neuraminyl 2 3 beta galactosyl 1 3) N acetylgalactosaminide alpha 2 6 sialyltransferase 1 antibody; ST6GalNAc I antibody; ST6GALNAC1 antibody; ST6GalNAcI antibody; STYI antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 protein (36-249AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，ST6GALNAC1 Antibody (CSB-PA868312LA01HU)，的標記方式是Non-conjugated。對于ST6GALNAC1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應用
    HRP CSB-PA868312LB01HU ST6GALNAC1 Antibody, HRP conjugated ELISA
    FITC CSB-PA868312LC01HU ST6GALNAC1 Antibody, FITC conjugated
    Biotin CSB-PA868312LD01HU ST6GALNAC1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 基因功能參考文獻：
    1. Our results indicated that ST6GALNAC1 was downregulated in sporadic esophageal squamous cell carcinoma via hyper-methylation and loss of heterozygosity , and it may be a candidate responsible gene for esophageal squamous cell carcinoma PMID: 28035351
    2. ST6GalNAc I regulates the gene expression of IGF-1 through STAT5b activation and plays role in gastric cancer invasion and metastasis. PMID: 25532910
    3. upregulated Siat7A expression, which was paralleled by the increased Klf4 in the ischemic myocardium, contributed to cardiomyocyte apoptosis following myocardial infarction PMID: 25860962
    4. Using qRT-PCR, sialyl-Tn expression was found to be associated with an increase in alpha2,6-sialyltransferase gene (ST6GALNAC1) and a decrease in core 1 synthase gene (C1GALT1) in LS174T cells. PMID: 24840470
    5. It was confirmed that MUC1 carries sialyl Tn also in human advanced gastric cancer tissues PMID: 22228572
    6. The stable transfection of MDA-MB-231 with an expression vector encoding ST6GalNAc I induces the expression of STn antigen at the cell surface. PMID: 12820722
    7. ST6GalNAc-I sialyltransferase localizes throughout the Golgi and has a role in synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer PMID: 16319059
    8. Expression of ppGalNAc-T6 is significantly higher in breast cancer compared to 'normal'/benign breast tissue samples. ST6GalNAc-I expression in breast cancer is associated with better prognosis. PMID: 19287074

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  • 亞細胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 29 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 23614

    OMIM: 610138

    KEGG: hsa:55808

    STRING: 9606.ENSP00000156626

    UniGene: Hs.105352