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SULT1A2 Antibody, HRP conjugated

  • 中文名稱：
    SULT1A2兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA022934LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SULT1A2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SULT1A2
  • 別名：
    Aryl sulfotransferase 2 antibody; Arylamine sulfotransferase antibody; HAST4 antibody; MGC142287 antibody; MGC142289 antibody; P PST antibody; P-PST 2 antibody; Phenol preferring phenol sulfotransferase 2 antibody; Phenol sulfotransferase 2 antibody; Phenol-sulfating phenol sulfotransferase 2 antibody; Phenolic metabolizing (P) form of PST antibody; ST1A2 antibody; ST1A2_HUMAN antibody; STP2 antibody; Sulfotransferase 1A2 antibody; Sulfotransferase family cytosolic 1A phenol preferring member 2 antibody; SULT1A2 antibody; Thermostable phenol sulfotransferase antibody; TSPST2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Sulfotransferase 1A2 protein (195-284AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfonation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.
  • 基因功能參考文獻(xiàn)：
    1. Suggest SULT1A1/1A2 play a central role in furfuryl alcohol bioactivation and the formation of hemoglobin adducts. PMID: 29908303
    2. The polymorphism of SULT1A2*2 is not associated with esophageal squamous cell carcinoma risk. PMID: 26455829
    3. SULT1A2 genotype also seems to play an important role in maintaining optimal levels of both 4OH-TAM and endoxifen. PMID: 23922954
    4. resequenced the SULT1A2 and SULT1A2 genes and identified 51 variations in ethnic Koreans, including 9 that were previously unknown. Allele frequencies, haplotype structures, LD blocks, and haplotype-tagging SNPs were determined. PMID: 23358261
    5. the statistical hypothesis that SULT1A1 and SULT1A2 alleles are independently distributed was rejected; a strongly positive linkage was detected between SULT1A1*2 and SULT1A2*2 alleles in Turkey population PMID: 20936502
    6. the structures of SULT1A2 and an allozyme of SULT1A1, SULT1A1 *3, bound with 3'-phosphoadenosine 5'-phosphate at 2.4 and 2.3A resolution, respectively, were determined. PMID: 20417180
    7. SULT1A2 polymorphisms in 230 Taiwanese breast cancer patients PMID: 12373301
    8. the relationship among the polymorphisms of this enzyme and SULT1A1 in different types of cancers in Taiwanese PMID: 12469224
    9. SULT1A1*2 and SULT1A2*2 are the major allelic variants in the Korean population PMID: 16133548
    10. SULT1A1/SULT1A2 gene complex showed suggestive haplotypic association in the family-based cardiovascular disease study, with the greatest increase in risk conferred by the SULT1A2 235T allele PMID: 18259693

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  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Sulfotransferase 1 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11454

    OMIM: 601292

    KEGG: hsa:6799

    STRING: 9606.ENSP00000338742

    UniGene: Hs.546304