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SYT6 Antibody

  • 中文名稱:
    SYT6兔多克隆抗體
  • 貨號(hào):
    CSB-PA716356LA01HU
  • 規(guī)格:
    ¥440
  • 促銷:
    小規(guī)格抗體限時(shí)一口價(jià)
  • 圖片:
    • Immunofluorescence staining of MCF-7 cells with CSB-PA716356LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) SYT6 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SYT6
  • 別名:
    Synaptotagmin 6 antibody; Synaptotagmin VI antibody; Synaptotagmin-6 antibody; Synaptotagmin6 antibody; SynaptotagminVI antibody; Syt 6 antibody; Syt VI antibody; SYT6 antibody; SYT6_HUMAN antibody; SytVI antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Synaptotagmin-6 protein (104-425AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁面中的產(chǎn)品,SYT6 Antibody (CSB-PA716356LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于SYT6 Antibody,我們還提供其他標(biāo)記。見下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA716356LB01HU SYT6 Antibody, HRP conjugated ELISA
    FITC CSB-PA716356LC01HU SYT6 Antibody, FITC conjugated
    Biotin CSB-PA716356LD01HU SYT6 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm.
  • 基因功能參考文獻(xiàn):
    1. synaptotagmin must be dephosphorylated at a specific window of time and phosphorylated synaptotagmin has an active role at early stages of the acrosomal exocytosis. PMID: 20551332
    2. Acrosomal exocytosis is regulated through the PKC-mediated phosphorylation of conserved threonines in the polybasic regions of synaptotagmin VI. PMID: 16111671
    3. SYT6 is hypermethylated in renal cell carcinoma. PMID: 18639284
  • 亞細(xì)胞定位:
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein.; [Isoform 1]: Membrane; Single-pass membrane protein.; [Isoform 2]: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein.
  • 蛋白家族:
    Synaptotagmin family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 18638

    OMIM: 607718

    KEGG: hsa:148281

    STRING: 9606.ENSP00000358559

    UniGene: Hs.370963