TACC2 Antibody
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中文名稱:TACC2兔多克隆抗體
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貨號:CSB-PA235316
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規(guī)格:¥1100
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圖片:
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:TACC2
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別名:TACC2 antibody; Transforming acidic coiled-coil-containing protein 2 antibody; Anti-Zuai-1 antibody; AZU-1 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human,Mouse
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免疫原:Synthetic peptide of Human TACC2
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:Antigen affinity purification
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA,IHC
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推薦稀釋比:
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:25-1:100 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
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功能:Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors. May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker.
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基因功能參考文獻(xiàn):
- This finding suggests that TACC2 may be a useful tool as a candidate biomarker to predict the recurrence and prognosis of hepatocellular carcinoma. PMID: 29843208
- These results suggest that TACC2 plays an important role in the cell proliferation of breast carcinoma and therefore immunohistochemical TACC2 status is a candidate of worse prognostic factor in breast cancer cases. PMID: 27333920
- Differential expression of the transcripts TACC2 connects ubiquitin-proteasome system with infection-inflammation in preterm births and preterm premature rupture of membranes. PMID: 25884766
- Data suggest that TACC2 is highly expressed in prostate cancer cells and contributes to cell cycle progression and cell proliferation in androgen-nonresponsive prostate cancer cells; overexpression of TACC2 leads to recurrence of prostate cancer. PMID: 22456197
- Results revealed 3 genes highly predictive of event-free survival (EFS), beyond age and MLL status: FLT3, IRX2, and TACC2. PMID: 22210879
- TACC2 may mediate an oncogenic effect on breast cancer cells. PMID: 20335520
- Defects in TACC2 expression may affect gene regulation, thus contributing to the pathogenesis of some tumors. PMID: 12620397
- GCN5L2 is a TACC2-binding protein. PMID: 14767476
- Centrosomal TACC2 is required for mitotic spindle maintenance. PMID: 15304323
- Simian virus 40 large T antigen interacting with TACC2 is involved in stabilizing microtubules in mitosis. PMID: 19671663
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亞細(xì)胞定位:Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
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蛋白家族:TACC family
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組織特異性:Strongly expressed in heart, skeletal muscle, brain, prostate, thyroid and trachea.
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