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TECPR1 Antibody, Biotin conjugated

  • 中文名稱：
    TECPR1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA773603LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TECPR1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TECPR1
  • 別名：
    2210010N04Rik antibody; DKFZP434B0335 antibody; FLJ23419 antibody; FLJ90593 antibody; KIAA1358 antibody; MGC124730 antibody; mKIAA1358 antibody; RGD1306873 antibody; TCPR1_HUMAN antibody; Tecpr1 antibody; tectonin beta propeller repeat containing 1 antibody; Tectonin beta-propeller repeat-containing protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Tectonin beta-propeller repeat-containing protein 1 protein (199-487AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
  • 基因功能參考文獻：
    1. The concerted interactions among TECPR1, Atg12-Atg5, and PtdIns(3)P provide the fusion specificity between autophagosomes and lysosomes and that the assembly of this complex initiates the autophagosome maturation process. PMID: 22342342
  • 亞細胞定位：
    Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes.
  • 蛋白家族：
    TECPR1 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 22214

    OMIM: 614781

    KEGG: hsa:25851

    STRING: 9606.ENSP00000404923

    UniGene: Hs.592281