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THRSP Antibody, Biotin conjugated

  • 中文名稱:
    THRSP兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA846095LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) THRSP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    THRSP
  • 別名:
    Lpgp antibody; LPGP1 antibody; MGC21659 antibody; OTTHUMP00000233866 antibody; S14 antibody; S14 protein antibody; SPOT 14 antibody; Spot 14 protein antibody; SPOT14 antibody; SPOT14 homolog antibody; Thrsp antibody; THRSP_HUMAN antibody; Thyroid hormone inducible hepatic protein antibody; Thyroid hormone responsive (SPOT14 homolog rat) antibody; Thyroid hormone responsive antibody; Thyroid hormone responsive protein antibody; Thyroid hormone responsive SPOT14 antibody; Thyroid hormone-inducible hepatic protein antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Thyroid hormone-inducible hepatic protein (41-144AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
  • 基因功能參考文獻(xiàn):
    1. The results of the present study indicated that Spot14/S14R were differently expressed in MSC adipogenesis in AIS patients, and they may be important in the abnormal adipogenic differentiation in AIS. PMID: 27082501
    2. In human breast cancer cell lines, S14 expression was highest in those representing the luminal subtype compared to those cell lines with basal characteristics. PMID: 25472762
    3. N-terminally truncated human Thrsp and its selenomethionyl derivative were collected to 4.0, 3.0 and 3.6 A resolution PMID: 21821901
    4. significantly greater thyroid hormone response for the human promoter, compared with the rat. PMID: 12960053
    5. human Spot 14 protein might regulate the p53 target gene, p21(WAF1/Cip1), via its direct interaction with the thyroid receptor or other p53 coactivators, such as Zac1. PMID: 18299245

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  • 亞細(xì)胞定位:
    Nucleus. Cytoplasm.
  • 蛋白家族:
    SPOT14 family
  • 組織特異性:
    Mainly expressed in tissues that synthesize triglycerides.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 11800

    OMIM: 601926

    KEGG: hsa:7069

    STRING: 9606.ENSP00000281030

    UniGene: Hs.591969